United States
Germany
Japan
United Kingdom
China
ALOXE3 (NM_001165960) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC228595L3V
- LentiORF®
-
Lenti ORF particles, ALOXE3 (Myc-DDK-tagged)-Human arachidonate lipoxygenase 3 (ALOXE3), transcript variant 1, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 15,390.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | ALOXE3 (NM_001165960) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ARCI3; E-LOX; eLOX-3; eLOX3 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001165960 |
| ORF Size | 2529 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC228595).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001165960.1, NP_001159432.1 |
| RefSeq ORF | 2532 bp |
| Locus ID | 59344 |
| Protein Families | Druggable Genome |
| MW | 95 kDa |
| Gene Summary | This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
