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ALOXE3 (NM_001165960) Human Untagged Clone
CAT＃: SC327230
ALOXE3 (untagged)-Human arachidonate lipoxygenase 3 (ALOXE3) transcript variant 1
CNY 16,340.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARCI3; E-LOX; eLOX-3; eLOX3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001165960, the custom clone sequence may differ by one or more nucleotides
ATGCCACGCGGGGCATTCAGACCCTGTTTGCCGGCGCTGTATTTCGCTTTCCTGACCTGC CCTACTCCAGAGCAGAGAATGAGTGGAACCCAGGCTCCTGATATCCATCTGGGTGAGCCA GCCAGAGGGACCGGCTGTGTCAGAGGCAAGCAAACAAGTATTAGAGTGCAAGACTGTGGG CGGAGAGAGGAAGCCCGAGCCGCCAGCAGGGAGCTTCGGAGAGAGAAAGCCCAGGAACAT CCCAGAGAGAGCTGGGCCCATCCTCAGCCCTACCCAGCCCCGCAGCCCCTAGCCCTCCGC CCAGAAACCCAGCCCTGTCCGGCGTGCCGCTCTTCTCCTCCAGGCCGGCTGCTGCTGCGG CCAGCGTTGCCGGGGCATCCCTTCCTCCTTCCCATCATGGCAGTGTACCGCCTGTGTGTG ACCACTGGTCCCTACCTGAGGGCCGGCACACTGGACAACATCTCTGTCACACTGGTGGGC ACGTGTGGTGAAAGCCCCAAGCAGCGGCTAGATCGAATGGGCAGGGACTTCGCCCCTGGA TCGGTACAGAAGTACAAGGTGCGTTGCACAGCGGAGCTGGGTGAGCTCTTGCTGCTGCGT GTACACAAGGAGCGCTACGCTTTCTTCCGCAAGGACTCTTGGTACTGTAGCCGCATCTGT GTCACCGAACCGGATGGTAGTGTATCCCACTTCCCCTGCTATCAGTGGATTGAAGGCTAC TGCACCGTGGAGCTGAGGCCAGGAACAGCAAGAACTATTTGTCAGGACTCTCTTCCCCTC CTCCTGGATCACAGGACACGGGAGCTCCGGGCCCGACAAGAATGCTACCGCTGGAAGATC TATGCCCCTGGCTTCCCCTGCATGGTAGACGTCAACAGCTTTCAGGAGATGGAGTCAGAC AAGAAATTTGCCTTGACAAAGACGACAACTTGTGTAGACCAGGGTGACAGCAGTGGGAAT CGGTACCTGCCCGGCTTCCCCATGAAAATTGACATCCCATCCCTGATGTACATGGAGCCC AATGTTCGATACTCAGCCACCAAGACGATCTCGCTGCTCTTCAATGCCATCCCTGCGTCC TTGGGAATGAAGCTTCGAGGGCTGTTGGATCGCAAGGGCTCCTGGAAGAAGCTGGATGAC ATGCAGAACATCTTCTGGTGCCATAAGACCTTCACGACAAAGTATGTCACAGAGCACTGG TGTGAAGATCACTTCTTTGGGTACCAGTACCTGAATGGTGTCAATCCCGTCATGCTCCAC TGCATCTCTAGCTTGCCCAGCAAGCTGCCTGTCACCAATGACATGGTGGCCCCCTTGCTG GGACAGGACACATGCCTGCAGACAGAGCTAGAGAGGGGGAACATCTTCCTAGCGGACTAC TGGATCCTGGCGGAGGCCCCCACCCACTGCCTAAACGGCCGCCAGCAGTACGTGGCCGCC CCACTGTGCCTGCTGTGGCTCAGCCCCCAGGGGGCGCTGGTGCCCTTGGCCATCCAGCTC AGCCAGACCCCCGGGCCTGACAGCCCCATCTTCCTGCCCACTGACTCCGAATGGGACTGG CTGCTGGCCAAGACGTGGGTGCGCAACTCTGAGTTCCTGGTGCACGAAAACAACACGCAC TTTCTGTGCACGCATTTGCTGTGCGAGGCCTTCGCCATGGCCACGCTGCGCCAGCTGCCG CTCTGCCACCCCATCTACAAGCTCCTACTCCCCCACACTCGATACACGCTGCAGGTGAAC ACCATCGCGAGGGCCACGCTGCTCAACCCCGAGGGCCTCGTGGACCAGGTCACGTCCATC GGGAGGCAAGGCCTCATCTACCTCATGAGCACGGGCCTGGCCCACTTCACCTACACCAAT TTCTGCCTTCCGGACAGCCTGCGGGCCCGCGGCGTCCTGGCTATCCCCAACTACCACTAC CGAGACGACGGCCTGAAGATCTGGGCGGCCATTGAGAGCTTTGTCTCAGAAATCGTGGGC TACTATTATCCCAGTGACGCATCTGTGCAGCAGGATTCGGAGCTGCAGGCCTGGACTGGC GAGATTTTTGCTCAGGCGTTCCTGGGCCGGGAAAGCTCAGGTTTCCCAAGCCGGCTGTGC ACCCCAGGAGAGATGGTGAAGTTCCTCACTGCAATCATCTTCAATTGCTCTGCCCAGCAC GCTGCTGTCAACAGTGGGCAGCATGACTTTGGGGCCTGGATGCCCAATGCTCCATCATCC ATGAGGCAGCCCCCACCCCAGACCAAGGGGACCACCACCCTGAAGACTTACCTAGACACC CTCCCTGAAGTGAACATCAGCTGTAACAACCTCCTCCTCTTCTGGTTGGTTAGCCAAGAA CCCAAGGACCAGAGGCCCCTGGGCACCTACCCAGATGAGCACTTCACAGAGGAGGCCCCG AGGCGGAGCATCGCCGCCTTCCAGAGCCGCCTGGCCCAGATCTCAAGGGACATCCAGGAG CGGAACCAGGGTCTGGCACTGCCCTACACCTACCTGGACCCTCCCCTCATTGAGAACAGC GTCTCCATC |
| Restriction Sites | Please inquire |
| ACCN | NM_001165960 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001165960.1, NP_001159432.1 |
| RefSeq Size | 3415 bp |
| RefSeq ORF | 2532 bp |
| Locus ID | 59344 |
| UniProt ID | Q9BYJ1 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC228595 | ALOXE3 (Myc-DDK-tagged)-Human arachidonate lipoxygenase 3 (ALOXE3), transcript variant 1 |
CNY 8,840.00 |
|
| RC228595L3 | Lenti-ORF clone of ALOXE3 (Myc-DDK-tagged)-Human arachidonate lipoxygenase 3 (ALOXE3), transcript variant 1 |
CNY 10,740.00 |
|
| RC228595L4 | Lenti-ORF clone of ALOXE3 (mGFP-tagged)-Human arachidonate lipoxygenase 3 (ALOXE3), transcript variant 1 |
CNY 10,740.00 |
|
| RG228595 | ALOXE3 (tGFP-tagged) - Human arachidonate lipoxygenase 3 (ALOXE3), transcript variant 1 |
CNY 9,690.00 |
