TCHP (NM_001143852) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC227291L4V
- LentiORF®
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Lenti ORF particles, TCHP (mGFP-tagged) - Human trichoplein, keratin filament binding (TCHP), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 10,640.00
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Specifications
Product Data | |
Product Name | TCHP (NM_001143852) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | TpMs |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001143852 |
ORF Size | 1494 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC227291).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001143852.1 |
RefSeq Size | 3111 bp |
RefSeq ORF | 1497 bp |
Locus ID | 84260 |
MW | 61.1 kDa |
Gene Summary | Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).[UniProtKB/Swiss-Prot Function] |
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