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NRDE2 (NM_017970) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC224847L1V
- LentiORF®
-
Lenti ORF particles, NRDE2 (Myc-DDK-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 11,210.00
货期*
3周
规格
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Specifications
| Product Data | |
| Product Name | NRDE2 (NM_017970) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | C14orf102 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_017970 |
| ORF Size | 3492 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC224847).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_017970.2 |
| RefSeq Size | 3824 bp |
| RefSeq ORF | 3495 bp |
| Locus ID | 55051 |
| MW | 132.5 kDa |
| Gene Summary | Protein of the nuclear speckles that regulates RNA degradation and export from the nucleus through its interaction with MTREX an essential factor directing various RNAs to exosomal degradation (PubMed:30842217). Changes the conformation of MTREX, precluding its association with the nuclear exosome and interaction with proteins required for its function in RNA exosomal degradation (PubMed:30842217). Negatively regulates, for instance, the degradation of mRNAs and lncRNAs by inhibiting their MTREX-mediated recruitment to nuclear exosome (PubMed:30842217). By preventing the degradation of RNAs in the nucleus, it promotes their export to the cytoplasm (PubMed:30842217).[UniProtKB/Swiss-Prot Function] |
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