pLenti-C-Myc-DDK Lentiviral Gene Expression Vector

CAT＃: PS100064

pLenti-C-Myc-DDK, Lenti vector with C-terminal Myc-DDK tag, 10ug

Datasheet
SDS
Vector Sequence

CNY 7,130.00

货期*
现货
规格
    • 10 ug
Cited in 72 publications.

Product images

经常一起买 (4)
TF81001
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00

添加到购物车
GE100111
Forward primer to sequence targets cloned in expression vectors.
    • 1 nmol

CNY 570.00

添加到购物车
GE100122
Reverse primer to sequence targets cloned in expression vectors.
    • 1 nmol

CNY 570.00

添加到购物车
TR30037
Lenti-vpak packaging kit - packaging plasmids and transfection reagent
    • 10 reactions

CNY 5,420.00

添加到购物车

Specifications

Product Data
C-Tag Myc-DDK
E. coli Selection Chloramphenicol (34 ug/mL)
Features

This Lenti vector is a third generation of lentiviral vector.

  • All OriGene’s TrueORF clone can be shuttled into this vector via PrecisionShuttling, a simple cut-and-ligation process.
  • The ORF cloned in this vector can be expressed as a tagged protein with c-terminal Myc-DDK tags
  • Lentiviral infection is a convenient way to delivery DNA into most cell lines and is uniquely effective for the non-dividing cells.
  • A brief lentiviral packaging protocol is provided.
  • V2_F Primer can be used to sequence the target sequence after cloning.
  • LR50 Primer can be used to sequence the target sequence after cloning.
Schematic of the multiple cloning sites
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (72)

The use of this Vectors has been cited in the following citations:
FAM46C Is an Interferon-Stimulated Gene That Inhibits Lentiviral Particle Production by Modulating Autophagy ,null, Microbiology Spectrum ,PubMed ID 37358411
Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2 ,null, Cellular and Molecular Gastroenterology and Hepatology ,PubMed ID 35840034
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs ,null, Basic Research in Cardiology ,PubMed ID 35737129
CES2 sustains HNF4α expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop ,null, Molecular Metabolism ,PubMed ID 34971802
The NOTCH3 Downstream Target HEYL Is Required for Efficient Human Airway Basal Cell Differentiation ,null, Cells ,PubMed ID 34831437
Fatty acid mobilization from adipose tissue is mediated by CD36 posttranslational modifications and intracellular trafficking ,null, JCI Insight ,PubMed ID 34314388
Tumor cell IDO enhances immune suppression and decreases survival independent of tryptophan metabolism in glioblastoma ,null, Clinical cancer research : an official journal of the American Association for Cancer Research ,PubMed ID 34479957
Pneumococcal surface adhesion A protein (PsaA) interacts with human Annexin A2 on airway epithelial cells ,null, Virulence ,PubMed ID 34233589
MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation ,Wittrahm, R;Takalo, M;Marttinen, M;Kuulasmaa, T;M?kinen, P;Kemppainen, S;Martiskainen, H;Rauramaa, T;Pike, I;Leinonen, V;Natunen, T;Haapasalo, A;Hiltunen, M;, Cells ,PubMed ID 33918872 [pLenti-CMV-C-Myc-DDK]
Secreted phosphoprotein-1 accelerates the progression of human colorectal cancer through activating β-catenin signaling ,null, Oncology Letters ,PubMed ID 33777196
Schizophrenia-associated SLC39A8 polymorphism is a loss-of-function allele altering glutamate receptor and innate immune signaling ,null, Translational Psychiatry ,PubMed ID 33608496
A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance ,null, Oncogene ,PubMed ID 33420373
The Alzheimer\'s disease-associated protective Plcγ2-P522R variant promotes immune functions ,Takalo, M;Wittrahm, R;Wefers, B;Parhizkar, S;Jokivarsi, K;Kuulasmaa, T;Mäkinen, P;Martiskainen, H;Wurst, W;Xiang, X;Marttinen, M;Poutiainen, P;Haapasalo, A;Hiltunen, M;Haass, C;, Molecular neurodegeneration ,PubMed ID 32917267 [pLenti-C-Myc-DDK]
Targeting cluster of differentiation 47 improves the efficacy of anti-cytotoxic T-lymphocyte associated protein 4 treatment via antigen presentation enhancement in pancreatic ductal adenocarcinoma ,null, Experimental and Therapeutic Medicine ,PubMed ID 32855701
Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis ,Davis, JC;Alves, TC;Helman, A;Chen, JC;Kenty, JH;Cardone, RL;Liu, DR;Kibbey, RG;Melton, DA;, Cell Rep ,PubMed ID 32402282 [pLenti-C-Myc-DDK]
The Alzheimer′ s disease-associated protective Plcγ2-P522R variant promotes beneficial microglial functions ,Takalo, M;Wittrahm, R;Wefers, B;Parhizkar, S;, bioRxiv [pLenti-C-Myc-DDK]
Spi-C positively regulates RANKL-mediated osteoclast differentiation and function ,null, Experimental & Molecular Medicine ,PubMed ID 32341419
Deguelin suppresses non-small cell lung cancer by inhibiting EGFR signaling and promoting GSK3β/FBW7-mediated Mcl-1 destabilization ,Gao, F;Yu, X;Li, M;Zhou, L;Liu, W;Li, W;Liu, H;, Cell Death Dis ,PubMed ID 32081857 [pLenti-C-Myc-DDK]
The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13 ,Mulas, F;Wang, X;Song, S;Nishanth, G;Yi, W;Brunn, A;Larsen, PK;Isermann, B;Kalinke, U;Barragan, A;Naumann, M;Deckert, M;Schlüter, D;, Cell. Mol. Immunol. ,PubMed ID 32024978 [pLenti-C-Myc-DDK]
The G3BP1-Family-USP10 Deubiquitinase Complex Rescues Ubiquitinated 40S Subunits of Ribosomes Stalled in Translation from Lysosomal Degradation. ,null, Molecular cell ,PubMed ID 31981475
Effects of Galectin-1 on Biological Behavior in Cervical Cancer ,null, Journal of Cancer ,PubMed ID 32047564
Retinoid receptor turnover mediated by sumoylation, ubiquitination and the valosin-containing protein is disrupted in glioblastoma ,Rodriguez, V;Bailey, R;Larion, M;Gilbert, MR;, Sci Rep ,PubMed ID 31700049 [pLenti-C-Myc-DDK]
Intestinal Epithelial Cells Exposed to Bacteroides fragilis Enterotoxin Regulate NF-κB Activation and Inflammatory Responses through β-Catenin Expression ,null, Infection and Immunity ,PubMed ID 31451622
SLUG Directs the Precursor State of Human Brain Tumor Stem Cells ,Chesnelong, C;Hao, X;Cseh, O;Wang, AY;Luchman, HA;Weiss, S;, Cancers (Basel) 2019 ,PubMed ID 31652994 [pLenti-C-Myc-DDK]
Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing ,Mahmoudi, S;Mancini, E;Xu, L;Moore, A;Jahanbani, F;Hebestreit, K;Srinivasan, R;Li, X;Devarajan, K;Prélot, L;Ang, CE;Shibuya, Y;Benayoun, BA;Chang, ALS;Wernig, M;Wysocka, J;Longaker, MT;Snyder, MP;Brunet, A;, Nature ,PubMed ID 31645721 [pLenti-C-Myc-DDK]
Eutherian-specific gene TRIML2 attenuates inflammation in the evolution of placentation ,Zhang, X;Pavlicev, M;Jones, HN;Muglia, LJ;, Mol. Biol. Evol. ,PubMed ID 31633784 [pLenti-C-Myc-DDK]
Mitofusin2 regulates the proliferation and function of fibroblasts: The possible mechanisms underlying pelvic organ prolapse development. ,null, Molecular medicine reports ,PubMed ID 31322173
Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00283a ,null, Chemical Science ,PubMed ID 31803422
Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment ,null, Nucleic Acids Research ,PubMed ID 30923829
The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis ,null, PLoS Pathogens ,PubMed ID 31181121
FGFR1β is a driver isoform of FGFR1 alternative splicing in breast cancer cells ,null, Oncotarget ,PubMed ID 30713601
CCNG1 (Cyclin G1) regulation by mutant-P53 via induction of Notch3 expression promotes high-grade serous ovarian cancer (HGSOC) tumorigenesis and progression ,Xu, Y;Zhang, Q;Miao, C;Dongol, S;Li, Y;Jin, C;Dong, R;Li, Y;Yang, X;Kong, B;, Cancer Med ,PubMed ID 30565428 [pLenti-C-Myc-DDK]
APOBEC3G-Regulated Host Factors Interfere with Measles Virus Replication: Role of REDD1 and Mammalian TORC1 Inhibition ,null, Journal of Virology ,PubMed ID 29925665
A mouse model engineered to conditionally express the progesterone receptor-B isoform ,Hai, L;Szwarc, MM;Wetendorf, M;Wu, SP;Peavey, MC;Grimm, SL;Edwards, DP;DeMayo, FJ;Lydon, JP;, Genesis ,PubMed ID 30004627 [pLenti-C-Myc-DDK]
αvβ5 integrin mediates the effect of vitronectin on the initial stage of differentiation in mouse cerebellar granule cell precursors ,Abe, A;Hashimoto, K;Akiyama, A;Iida, M;Ikeda, N;Hamano, A;Watanabe, R;Hayashi, Y;Miyamoto, Y;, Brain Res. ,PubMed ID 29702083 [pLenti-C-Myc-DDK]
Functional role of PLCE1 intronic insertion variant associated with susceptibility to esophageal squamous cell carcinoma. ,null, Carcinogenesis ,PubMed ID 29106514
Claudin-18–mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis ,null, The Journal of Clinical Investigation ,PubMed ID 29400695
STAT3/p53 pathway activation disrupts IFN- β–induced dormancy in tumor-repopulating cells ,null, The Journal of Clinical Investigation ,PubMed ID 29431732
The MTM1-UBQLN2-HSP complex mediates degradation of misfolded intermediate filaments in skeletal muscle ,Gavriilidis, C;Laredj, L;Solinhac, R;Messaddeq, N;Viaud, J;Laporte, J;Sumara, I;Hnia, K;, Nat. Cell Biol. ,PubMed ID 29358706 [pLenti-C-Myc-DDK]
SUSD2 promotes cancer metastasis and confers cisplatin resistance in high grade serous ovarian cancer. ,null, Experimental cell research ,PubMed ID 29305171
BrainPhys® increases neurofilament levels in CNS cultures, and facilitates investigation of axonal damage after a mechanical stretch-injury in vitro ,Jackson, TC;Kotermanski, SE;Jackson, EK;Kochanek, PM;, Exp. Neurol. ,PubMed ID 29199132 [pLenti-C-Myc-DDK]
ZIC2 Is Essential for Maintenance of Latency and Is a Target of an Immediate Early Protein during Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivation ,null, Journal of Virology ,PubMed ID 28835494
NLR Nod1 signaling promotes survival of BCR-engaged mature B cells through up-regulated Nod1 as a positive outcome ,null, The Journal of Experimental Medicine ,PubMed ID 28878001
Fasting inhibits colorectal cancer growth by reducing M2 polarization of tumor-associated macrophages ,Sun, P;Wang, H;He, Z;Chen, X;Wu, Q;Chen, W;Sun, Z;Weng, M;Zhu, M;Ma, D;Miao, C;, Oncotarget ,PubMed ID 29088814 [pLenti-C-Myc-DDK]
Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons ,Jackson, TC;Kotermanski, SE;Kochanek, PM;, Neuroscience ,PubMed ID 28818525 [pLenti-C-MYC-DDK]
Deletion of the Vaccinia Virus B1 Kinase Reveals Essential Functions of This Enzyme Complemented Partly by the Homologous Cellular Kinase VRK2 ,null, Journal of Virology ,PubMed ID 28515294
KIR2DL5 mutation and loss underlies sporadic dermal neurofibroma pathogenesis and growth ,null, Oncotarget ,PubMed ID 28548933
Linking of mPGES-1 and iNOS activates stem-like phenotype in EGFR-driven epithelial tumor cells ,Terzuoli, E;Finetti, F;Costanza, F;Giachetti, A;Ziche, M;Donnini, S;, Nitric Oxide ,PubMed ID 28257996 [pLenti-C-Myc-DDK]
The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic Activity in Hepatic Stellate Cells Through Autophagy ,Kim, RS;Hasegawa, D;Goossens, N;Tsuchida, T;Athwal, V;Sun, X;Robinson, CL;Bhattacharya, D;Chou, HI;Zhang, DY;Fuchs, BC;Lee, Y;Hoshida, Y;Friedman, SL;, Sci Rep ,PubMed ID 27996033 [pLenti-C-Myc-DDK]
MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway ,Chen, W;Xu, Y;Zhong, J;Wang, H;Weng, M;Cheng, Q;Wu, Q;Sun, Z;Jiang, H;Zhu, M;Ren, Y;Xu, P;Chen, J;Miao, C;, Oncotarget ,PubMed ID 27783989 [pLenti-C-Myc-DDK]
Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation ,Stellos, K;Gatsiou, A;Stamatelopoulos, K;Perisic Matic, L;John, D;Lunella, FF;Jaé, N;Rossbach, O;Amrhein, C;Sigala, F;Boon, RA;Fürtig, B;Manavski, Y;You, X;Uchida, S;Keller, T;Boeckel, JN;Franco-Cereceda, A;Maegdefessel, L;Chen, W;Schwalbe, H;Bindereif, A;Eriksson, P;Hedin, U;Zeiher, AM;Dimmeler, S;, Nat. Med. ,PubMed ID 27595325
Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury ,Pedigo, CE;Ducasa, GM;Leclercq, F;Sloan, A;Mitrofanova, A;Hashmi, T;Molina-David, J;Ge, M;Lassenius, MI;Forsblom, C;Lehto, M;Groop, PH;Kretzler, M;Eddy, S;Martini, S;Reich, H;Wahl, P;Ghiggeri, G;Faul, C;Burke, GW;Kretz, O;Huber, TB;Mendez, AJ;Merscher, S;Fornoni, A;, J. Clin. Invest. ,PubMed ID 27482889
FOXD1-ALDH1A3 signaling is a determinant for the self-renewal and tumorigenicity of mesenchymal glioma stem cells ,Cheng, P;Wang, J;Waghmare, I;Sartini, S;Coviello, V;Kim, S;Mohyeldin, A;Pavlyukov, MS;Zhang, Z;Minata, M;Valentim, CL;Chhipa, RR;Bhat, KP;Dasgupta, B;La Motta, C;Kango-Singh, M;Nakano, I;, Cancer Res. ,PubMed ID 27569208
HER2 drives Mucin-like 1 to control proliferation in breast cancer cells ,null, Oncogene ,PubMed ID 26725324
Bacteroides fragilis Enterotoxin Upregulates Heme Oxygenase-1 in Intestinal Epithelial Cells via a Mitogen-Activated Protein Kinase- and NF-κB-Dependent Pathway, Leading to Modulation of Apoptosis ,null, Infection and Immunity ,PubMed ID 27324483
Miz1, a Novel Target of ING4, Can Drive Prostate Luminal Epithelial Cell Differentiation ,null, The Prostate ,PubMed ID 27527891
Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphatase ,null, Oncogene ,PubMed ID 27065332
Serine/Threonine kinase MLK4 determines Mesenchymal Identity in Glioma Stem Cells in an NF-κB-dependent manner ,null, Cancer cell ,PubMed ID 26859459
Potential role of TRIM3 as a novel tumour suppressor in colorectal cancer (CRC) development ,Piao, MY;Cao, HL;He, NN;Xu, MQ;Dong, WX;Wang, WQ;Wang, BM;Zhou, B;, Scand. J. Gastroenterol. ,PubMed ID 26691157 [PS100064]
UHRF1 promotes human osteosarcoma cell invasion by downregulating the expression of E-cadherin in an Rb1-dependent manner ,Liu, W;Qiao, RH;Wang, DM;Huang, XW;Li, B;Wang, D;, Mol Med Rep ,PubMed ID 26548607 [PS100064]
Targeted Deep Sequencing Identifies Rare ‘loss-of-function’ Variants in IFNGR1 for Risk of Atopic Dermatitis Complicated by Eczema Herpeticum ,null, The Journal of allergy and clinical immunology ,PubMed ID 26343451
Loss of protocadherin-17 (PCDH-17) promotes metastasis and invasion through hyperactivation of EGFR/MEK/ERK signaling pathway in hepatocellular carcinoma ,Dang, Z;Shangguan, J;Zhang, C;Hu, P;Ren, Y;Lv, Z;Xiang, H;Wang, X;, Tumour Biol. ,PubMed ID 26386721 [PS100064]
SLC9A3R1 stimulates autophagy via BECN1 stabilization in breast cancer cells ,null, Autophagy ,PubMed ID 26218645
EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function ,Phuchareon, J;McCormick, F;Eisele, DW;Tetsu, O;, Proc. Natl. Acad. Sci. U.S.A. ,PubMed ID 26150526 [PS100064]
Microenvironmental interleukin-6 suppresses toll-like receptor signaling in human leukemia cells through miR-17/19A. ,null, Blood ,PubMed ID 26041742
Flow-dependent expression of ectonucleotide tri(di)phosphohydrolase-1 and suppression of atherosclerosis ,Kanthi, Y;Hyman, MC;Liao, H;Baek, AE;Visovatti, SH;Sutton, NR;Goonewardena, SN;Neral, MK;Jo, H;Pinsky, DJ;, J. Clin. Invest. ,PubMed ID 26121751 [PS100064]
TAT-RasGAP317-326-mediated tumor cell death sensitization can occur independently of Bax and Bak. ,null, Apoptosis : an international journal on programmed cell death ,PubMed ID 24362790
Nicotine increases the resistance of lung cancer cells to cisplatin through enhancing Bcl-2 stability ,null, British Journal of Cancer ,PubMed ID 24548862
Suppression of anoikis in human intestinal epithelial cells: differentiation state-selective roles of α2β1, α3β1, α5β1, and α6β4 integrins ,null, BMC Cell Biology ,PubMed ID 24289209
Ribophorin II regulates breast tumor initiation and metastasis through the functional suppression of GSK3ß OPEN ,Ryou-u Takahashi, Fumitaka Takeshita, Kimi Honma, Masaya Ono, Kikuya Kato & Takahiro Ochiya, Scientific Reports 3, doi:10.1038/srep02474 ,PubMed ID 23959174 [pLenti-C-Myc-DDK]
Lentivirus mediated GOLPH3 shRNA inhibits growth and metastasis of esophageal squamous cancer. ,null, Asian Pacific journal of cancer prevention : APJCP ,PubMed ID 24175832
Evidence for Alteration of Gene Regulatory Networks through MicroRNAs of the HIV-Infected Brain: Novel Analysis of Retrospective Cases ,null, PLoS ONE ,PubMed ID 20436668

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