United States
Germany
Japan
United Kingdom
China
MED12 (NM_005120) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC217206L1V
- LentiORF®
-
Lenti ORF particles, MED12 (Myc-DDK tagged) - Human mediator complex subunit 12 (MED12), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 21,660.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | MED12 (NM_005120) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ARC240; CAGH45; FGS1; HOPA; Kto; MED12S; OHDOX; OKS; OPA1; TNRC11; TRAP230 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_005120 |
| ORF Size | 6531 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC217206).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_005120.2 |
| RefSeq Size | 6757 bp |
| RefSeq ORF | 6534 bp |
| Locus ID | 9968 |
| Protein Families | Druggable Genome |
| MW | 242.9 kDa |
| Gene Summary | The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
