ASAH2 (NM_019893) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC215027L4V
- LentiORF®
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Lenti ORF particles, ASAH2 (mGFP-tagged)-Human N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 (ASAH2), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 17,765.00
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Specifications
Product Data | |
Product Name | ASAH2 (NM_019893) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | BCDase; HNAC1; LCDase; N-CDase; NCDase |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_019893 |
ORF Size | 2340 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC215027).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_019893.1, NP_063946.2 |
RefSeq Size | 2289 bp |
RefSeq ORF | 2343 bp |
Locus ID | 56624 |
Protein Families | Transmembrane |
Protein Pathways | Metabolic pathways, Sphingolipid metabolism |
MW | 83.1 kDa |
Gene Summary | Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008] |
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