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PRCP (NM_199418) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC212658L2V
- LentiORF®
-
Lenti ORF particles, PRCP (mGFP-tagged) - Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 10,830.00
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规格
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Specifications
| Product Data | |
| Product Name | PRCP (NM_199418) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | HUMPCP; PCP |
| Vector | pLenti-C-mGFP |
| ACCN | NM_199418 |
| ORF Size | 1551 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC212658).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_199418.2 |
| RefSeq Size | 2224 bp |
| RefSeq ORF | 1554 bp |
| Locus ID | 5547 |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| MW | 55.7 kDa |
| Gene Summary | This gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. A pseudogene of this gene has been identified on chromosome 2. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
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