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PRCP (NM_199418) Human Untagged Clone
CAT＃: SC128292
PRCP (untagged)-Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2
CNY 3,856.00
CNY 8,360.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HUMPCP; PCP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC128292 sequence for NM_199418 edited (data generated by NextGen Sequencing)
ATGGGCCGCCGAGCCCTCCTGCTCCTGCTTCTGTCTTTTCTGGCGCCCTGGGCCACCATA GCCCTCCGGCCGGCCTTAAGGGCCCTCGGCAGCCTACACTTGCCAACCAACCCCACATCC CTCCCGGCTGTAGCCAAGAACTATTCGGTTCTCTACTTCCAACAGAAGGCCCTTGCTGCT GGGCAGTTGCACATATGTATTATCCAACTAAATCATTACAAGACTCCTCTGGTTGATCAT TTTGGATTTAATACTGTGAAAACTTTTAATCAGCGGTACCTAGTAGCTGATAAATACTGG AAGAAAAATGGTGGATCAATACTTTTCTACACTGGTAATGAAGGGGACATTATCTGGTTT TGTAATAACACGGGGTTCATGTGGGATGTGGCTGAGGAACTGAAAGCTATGTTGGTGTTT GCTGAACATCGATACTATGGAGAGTCTCTCCCCTTTGGTGACAACTCATTCAAGGATTCC AGACACTTGAATTTCCTGACATCAGAACAAGCTCTGGCTGATTTTGCAGAGTTAATCAAA CACTTGAAAAGAACAATCCCAGGAGCTGAAAATCAACCTGTCATTGCCATAGGAGGCTCC TATGGTGGCATGCTTGCCGCCTGGTTTAGGATGAAATATCCTCATATGGTAGTTGGAGCT CTTGCAGCTTCTGCCCCTATCTGGCAGTTTGAGGATTTAGTACCTTGTGGTGTATTTATG AAGATCGTAACTACAGATTTTAGGAAAAGCGGTCCACATTGTTCAGAGAGCATCCACAGG TCCTGGGATGCCATTAATCGACTCTCAAATACTGGCAGTGGTTTGCAGTGGCTTACTGGA GCCCTTCACTTATGCAGCCCATTAACTTCTCAGGACATCCAACATTTGAAAGACTGGATC TCTGAAACCTGGGTGAATCTGGCAATGGTGGACTATCCTTATGCCTCTAACTTTTTACAG CCTTTGCCTGCTTGGCCTATCAAGGTAGTGTGCCAGTATTTGAAAAATCCCAATGTATCT GATTCACTGCTGCTGCAGAATATTTTCCAAGCTCTGAATGTATATTACAATTATTCGGGC CAGGTGAAATGCCTGAATATTTCAGAGACAGCAACTAGCAGTCTGGGAACACTGGGTTGG AGCTATCAGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATG TTTGAACCTCACTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGT GTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGGCAAAAACATTAGTTCACAC ACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAG GATATCACAGACACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTC CGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGTTAGA CATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGA Clone variation with respect to NM_199418.2 >OriGene 5' read for NM_199418 unedited
GCATTGTATACGACTCCTATAGGGCGGCCGCGAATCGGCACGAGATGGGCCGCCGAGCCC TCCTGCTCCTGCTTCTGTCTTTTCTGGCGCCCTGGGCCACCATAGCCCTCCGGCCGGCCT TAAGGGCCCTCGGCAGCCTACACTTGCCAACCAACCCCACATCCCTCCCGGCTGTAGCCA AGAACTATTCGGTTCTCTACTTCCAACAGAAGGCCCTTGCTGCTGGGCAGTTGCACATAT GTATTATCCAACTAAATCATTACAAGACTCCTCTGGTTGATCATTTTGGATTTAATACTG TGAAAACTTTTAATCAGCGGTACCTAGTAGCTGATAAATACTGGAAGAAAAATGGTGGAT CAATACTTTTCTACACTGGTAATGAAGGGGACATTATCTGGTTTTGTAATAACACGGGGT TCATGTGGGATGTGGCTGAGGAACTGAAAGCTATGTTGGTGTTTGCTGAACATCGATACT ATGGAGAGTCTCTCCCCTTTGGTGACAACTCATTCAAGGATTCCAGACACTTGAATTTCC TGACATCAGAACAAGCTCTGGCTGATTTTGCAGAGTTAATCAAACACTTGAAAAGAACAA TCCCAGGAGCTGAAAATCAACCTGTCATTGCCATAGGAGGCTCCTATGGTGGCATGCTTG CCGCCTGGTTTAGGATGAAATATCCTCATATGGTAGTTGGAGCTCTTGCAGCTTCTGCCC CTATCTGGCAGTTTGAGGATTTAGTACCTTGTGGTGTATTTATGAAGATCGTAACTACAG ATTTTAGAAAAGCGGTCCACATTGTTCAGAGAGCATCCACAAGGTCCTGGGATGCCATTA ATCGACTCTCAATACTGGCAGTGGTTTGCAGTGGCCTTACTGGAGCCCTTCACCTTATGC AGCCCATTAACTTCCTCAGGACCATC |
| Restriction Sites | Please inquire |
| ACCN | NM_199418 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_199418.2, NP_955450.2 |
| RefSeq Size | 2224 bp |
| RefSeq ORF | 1554 bp |
| Locus ID | 5547 |
| UniProt ID | P42785 |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Gene Summary | This gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. A pseudogene of this gene has been identified on chromosome 2. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] Transcript Variant: This variant (2) includes an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) is longer than isoform 1. This isoform (2) may undergo proteolytic processing similar to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212658 | PRCP (Myc-DDK-tagged)-Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2 |
CNY 3,848.00 |
|
| RC212658L1 | Lenti ORF clone of Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2, Myc-DDK-tagged |
CNY 6,248.00 |
|
| RC212658L2 | Lenti ORF clone of Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2, mGFP tagged |
CNY 6,370.00 |
|
| RC212658L3 | Lenti ORF clone of Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2, Myc-DDK-tagged |
CNY 6,370.00 |
|
| RC212658L4 | Lenti ORF clone of Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2, mGFP tagged |
CNY 6,370.00 |
|
| RG212658 | PRCP (tGFP-tagged) - Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2 |
CNY 5,448.00 |
