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Jagged 2 (JAG2) (NM_002226) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC211925L1V
- LentiORF®
-
Lenti ORF particles, JAG2 (Myc-DDK tagged) - Human jagged 2 (JAG2), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 20,710.00
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规格
| Cited in 2 publications. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | Jagged 2 (JAG2) (NM_002226) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | HJ2; SER2 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_002226 |
| ORF Size | 3714 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC211925).
|
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_002226.3 |
| RefSeq Size | 5077 bp |
| RefSeq ORF | 3717 bp |
| Locus ID | 3714 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Notch signaling pathway |
| MW | 133.37 kDa |
| Gene Summary | The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Mutual regulation of JAG2 and PRAF2 promotes migration and invasion of colorectal cancer cells uncoupled from epithelial–mesenchymal transition
,null,
Cancer Cell International
,PubMed ID 31198409
[JAG2]
|
|
The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice
,null,
The Journal of Clinical Investigation
,PubMed ID 21403400
[JAG2]
|
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