LOXL1 (NM_005576) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC209830L1V
- LentiORF®
-
Lenti ORF particles, LOXL1 (Myc-DDK tagged) - Human lysyl oxidase-like 1 (LOXL1), 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
Product Data | |
Product Name | LOXL1 (NM_005576) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | LOL; LOXL |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_005576 |
ORF Size | 1722 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC209830).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_005576.2 |
RefSeq Size | 2361 bp |
RefSeq ORF | 1725 bp |
Locus ID | 4016 |
Domains | Lysyl_oxidase |
Protein Families | Secreted Protein |
MW | 63.17 kDa |
Gene Summary | This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome. [provided by RefSeq, Jan 2016] |
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