United States
Germany
Japan
United Kingdom
China
LOXL1 (NM_005576) Human Untagged Clone
CAT＃: SC116666
LOXL1 (untagged)-Human lysyl oxidase-like 1 (LOXL1)
CNY 6,424.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LOL; LOXL |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC116666 sequence for NM_005576 edited (data generated by NextGen Sequencing)
ATGGCTCTGGCCCGAGGCAGCCGGCAGCTGGGGGCCCTGGTGTGGGGCGCCTGCCTGTGC GTGCTGGTGCACGGGCAGCAGGCGCAGCCCGGGCAGGGCTCGGACCCCGCCCGCTGGCGG CAGCTGATCCAGTGGGAGAACAACGGGCAGGTGTACAGCTTGCTCAACTCGGGCTCAGAG TACGTGCCGGCCGGACCTCAGCGCTCCGAGAGTAGCTCCCGGGTGCTGCTGGCCGGCGCG CCCCAGGCCCAGCAGCGGCGCAGCCACGGGAGCCCCCGGCGTCGGCAGGCGCCGTCCCTG CCCCTGCCGGGGCGCGTGGGCTCGGACACCGTGCGCGGCCAGGCGCGGCACCCATTCGGC TTTGGCCAGGTGCCCGACAACTGGCGCGAGGTGGCCGTCGGGGACAGCACGGGCATGGCC CGGGCCCGCACCTCCGTCTCCCAGCAACGGCACGGGGGCTCCGCCTCCTCGGTCTCGGCT TCGGCCTTCGCCAGCACCTACCGCCAGCAGCCCTCCTACCCGCAGCAGTTCCCCTACCCG CAGGCGCCCTTCGTCAGCCAGTACGAGAACTACGACCCCGCGTCGCGGACCTACGACCAG GGTTTCGTGTACTACCGGCCCGCGGGCGGCGGCGTGGGCGCGGGGGCGGCGGCCGTGGCC TCGGCGGGGGTCATCTACCCCTACCAGCCCCGGGCGCGCTACGAGGAGTACGGCGGCGGC GAAGAGCTGCCCGAGTACCCGCCTCAGGGCTTCTACCCGGCCCCCGAGAGGCCCTACGTG CCGCCGCCGCCGCCGCCCCCCGACGGCCTGGACCGCCGCTACTCGCACAGTCTGTACAGC GAGGGCACCCCCGGCTTCGAGCAGGCCTACCCTGACCCCGGTCCCGAGGCGGCGCAGGCC CATGGCGGAGACCCACGCCTGGGCTGGTACCCGCCCTACGCCAACCCGCCGCCCGAGGCG TACGGGCCGCCGCGCGCGCTGGAGCCGCCCTACCTGCCGGTGCGCAGCTCCGACACGCCC CCGCCGGGTGGGGAGCGGAACGGCGCGCAGCAGGGCCGCCTCAGCGTGGGCAGCGTGTAC CGGCCCAACCAGAACGGCCGCGGTCTCCCTGACTTGGTCCCAGACCCCAACTATGTGCAA GCATCCACTTATGTGCAGAGAGCCCACCTGTACTCCCTGCGCTGTGCTGCGGAGGAGAAG TGTCTGGCCAGCACAGCCTATGCCCCTGAGGCCACCGACTACGATGTGCGGGTGCTACTG CGCTTCCCCCAGCGCGTGAAGAACCAGGGCACAGCAGACTTCCTCCCCAACCGGCCACGG CACACCTGGGAGTGGCACAGCTGCCACCAGCATTACCACAGCATGGACGAGTTCAGCCAC TACGACCTACTGGATGCAGCCACAGGCAAGAAGGTGGCCGAGGGCCACAAGGCCAGTTTC TGCCTGGAGGACAGCACCTGTGACTTCGGCAACCTCAAGCGCTATGCATGCACCTCTCAT ACCCAGGGCCTGAGCCCAGGCTGCTATGACACCTACAATGCGGACATCGACTGCCAGTGG ATCGACATAACCGACGTGCAGCCTGGGAACTACATCCTCAAGGTGCACGTGAACCCAAAG TATATTGTTTTGGAGTCTGACTTCACCAACAACGTGGTGAGATGCAACATTCACTACACA GGTCGCTACGTTTCTGCAACAAACTGCAAAATTGTCCAATCCTGA Clone variation with respect to NM_005576.2 >OriGene 5' read for NM_005576 unedited
GCACGAGGGAAAGCGCCAGCCGAGCGGCCAGCCAGTGCGGGGCTGGCCATGTAAGGCCCA CAGGCGGTCCTGCCCGCCCGGTGCCCTGCGGAGAGCCTCGTGCAGCCCTGGGCACCGCCC CTGCCCTGCCCTGACCCCTTGGCCTTGAAATGCTGTCATCGGAGGAGCCGTCCCGCTCGG GACAAGGCCAGCATGGACAAAGCTAGAGCTGGGGCAAGCAAGGAGCCTTCCTGTCCTCGA GGCCGTGGGAAGAGAAGCACGCCCAGGGGGCCACTCCTGAGAGCCTCTCTGTCCACCAGG CCTCTGCAGAGGGGTCACCATGGCTCTGGCCCGAGGCAGCCGGCAGCTGGGGGCCCTGGT GTGGGGCGCCTGCCTGTGCGTGCTGGTGCACGGGCAGCAGGCGCAGCCCGGGCAGGGCTC GGACCCCGCCCGCTGGCGGCAGCTGATCCAGTGGGAGAACAACGGGCAGGTGTACAGCTT GCTCAACTCGGGCTCAGAGTACGTGCCGGCCGGACCTCAGCGCTCCGAGAGTAGCTCCCG GGTGCTGCTGGCCGGCGCGCCCCAGGCCCAGCAGCGGCGCAGCCACGGGAGCCCCCGGCG TCGGCAGGCGCCGTCCCTGCCCCTGCCGGNGCGCGTGGGCTCGGACACCGT >OriGene 3' read for NM_005576 unedited
ACTTATGTACGCGGCCGCAATTTANGATCGATTTTTTTTCTTTTTTTNTTTTTAGAAAAA ACCTTGTTTTATTCAGCCCANACCTGGGCAATCTAGCTCTGTGGTATGGCCAAAGTATAA AAAATAAAAACCAACAACAACAAAACAACACTGTAGAGAAAAGTGAAGTATAAAATGGGG TCTGGCGTCCGGAATCCCTGTGGTTTTCATCCACGTTCGCTCCCTGAGGCCGGCAGGGAG GGATGCCCCTCCCTGCCTGTGGGTTGGGGGCTGGGCCCCTCGGCGGGAGGCTGCCCGGGG AGCAAGGCCTGCTTTGGAAGGGGAGAGATTGGCCATCTGTCCCTCCCGGAGATCAGGATT GGACAATTTTGCAGTTTGTTGCAGAAACGTAGCGACCTGTGTAGTGAATGTTGCATCTCA CCACGTTGTTGGTGAAGTCAGACTCCAAAACAATATACTTTGGGTTCACGTGCACCTTGA GGATGTAGTTCCCAGGCTGCACGTCGGTTATGTCGATCCACTGGCAGTCGATGTCCGCAT TGTAAGTGTCATAGCAGCCTGAGCTCAAGCCCTGGGTATGAGAGGTGCATGCATAGCGCT TGAGGTTGCCGAAGTCACAGGTGCTGTCCTCCAGGCAGAAACTGGCCTTGTGGCCCTCGG CCACCTTCTTGCCTGTGGCTGCATCCAGTAGGTCGTAATGGCTGAACTCGTCCATGCTGT GGTAATGCTGGTGGCAGCTGTGCCACTCCCAGGTGTGCCGTGGCCCGTTGGGGAGGAAGT CTGCTGTGCCCTGGTTCTCACGCGCTGGGGGAACGCANTAACACCCGACATCGTATTCCG TGGGCTCAGGGCATAAGCTGGGCTGGCANACACTTTTCCTCCGCACACAAGCAGGAGTTC AAGTGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005576 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005576.2, NP_005567.2 |
| RefSeq Size | 2361 bp |
| RefSeq ORF | 1725 bp |
| Locus ID | 4016 |
| UniProt ID | Q08397 |
| Domains | Lysyl_oxidase |
| Protein Families | Secreted Protein |
| Gene Summary | This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome. [provided by RefSeq, Jan 2016] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209830 | LOXL1 (Myc-DDK-tagged)-Human lysyl oxidase-like 1 (LOXL1) |
CNY 6,408.00 |
|
| RC209830L1 | Lenti ORF clone of Human lysyl oxidase-like 1 (LOXL1), Myc-DDK-tagged |
CNY 8,808.00 |
|
| RC209830L2 | Lenti ORF clone of Human lysyl oxidase-like 1 (LOXL1), mGFP tagged |
CNY 5,890.00 |
|
| RC209830L3 | Lenti ORF clone of Human lysyl oxidase-like 1 (LOXL1), Myc-DDK-tagged |
CNY 8,808.00 |
|
| RC209830L4 | Lenti ORF clone of Human lysyl oxidase-like 1 (LOXL1), mGFP tagged |
CNY 8,808.00 |
|
| RG209830 | LOXL1 (tGFP-tagged) - Human lysyl oxidase-like 1 (LOXL1) |
CNY 8,008.00 |
