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CENPB (NM_001810) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC208842L3V
- LentiORF®
-
Lenti ORF particles, CENPB (Myc-DDK-tagged)-Human centromere protein B, 80kDa (CENPB), 200ul, >10^7 TU/mL
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CNY 8,930.00
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规格
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Specifications
| Product Data | |
| Product Name | CENPB (NM_001810) Human Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001810 |
| ORF Size | 1797 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC208842).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001810.5 |
| RefSeq Size | 2856 bp |
| RefSeq ORF | 1800 bp |
| Locus ID | 1059 |
| Protein Families | Druggable Genome |
| MW | 65.2 kDa |
| Gene Summary | This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq, Jul 2008] |
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