Lipin 1 (LPIN1) (NM_145693) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC207138L1V
- LentiORF®
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Lenti ORF particles, LPIN1 (Myc-DDK-tagged)-Human lipin 1 (LPIN1), 200ul, >10^7 TU/mL
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CNY 8,930.00
Cited in 2 publications. |
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CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Product Name | Lipin 1 (LPIN1) (NM_145693) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | PAP1 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_145693 |
ORF Size | 2670 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC207138).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_145693.1 |
RefSeq Size | 5363 bp |
RefSeq ORF | 2673 bp |
Locus ID | 23175 |
Domains | lipin_N |
MW | 98.5 kDa |
Gene Summary | This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis
,null,
Cell Reports Medicine
,PubMed ID 34467247
[LPIN1]
|
Characterization of the Human LPIN1-encoded Phosphatidate Phosphatase Isoforms *
,null,
The Journal of Biological Chemistry
,PubMed ID 20231281
[LPIN1]
|
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