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Lipin 1 (LPIN1) (NM_145693) Human Untagged Clone
CAT＃: SC125492
LPIN1 (untagged)-Human lipin 1 (LPIN1)
CNY 6,528.00
| Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PAP1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_145693 edited
GGCAGCCGGCGGCGGGCTGGGTGTTTGCAATACAAAGGCGGCCACGCGCGGCGCCGCTCG GTGCAGACCATGAATTACGTGGGGCAGTTAGCCGGCCAGGTGTTTGTCACCGTGAAGGAG CTCTACAAGGGGCTGAATCCCGCCACACTCTCAGGGTGCATTGACATCATTGTCATCCGC CAGCCCAATGGAAACCTCCAATGCTCCCCTTTCCACGTCCGCTTTGGGAAGATGGGGGTC CTGCGCTCCCGAGAGAAAGTGGTTGACATAGAAATCAATGGGGAATCTGTGGATTTGCAT ATGAAATTGGGAGATAATGGAGAAGCATTTTTTGTTCAAGAAACAGATAATGATCAGGAA GTTATCCCTATGCACCTGGCCACCTCCCCCATCCTGTCAGAAGGAGCTTCGAGAATGGAA TGCCAGCTGAAAAGGGGCTCTGTGGACAGGATGAGAGGCCTGGACCCCAGCACGCCAGCC CAAGTGATCGCTCCCAGCGAGACGCCGTCAAGCAGCTCTGTAGTAAAGAAGAGAAGAAAA AGGAGGAGAAAGTCACAGCTGGACAGCCTGAAGAGAGATGACAACATGAACACATCTGAG GATGAGGACATGTTCCCCATCGAGATGAGCTCGGATGAGGCCATGGAGCTGCTGGAGAGC AGCAGAACTCTTCCTAATGATATACCTCCATTCCAAGATGATATTCCTGAGGAAAACCTC TCCCTGGCTGTGATTTACCCTCAGTCAGCCTCATACCCTAATTCGGATAGAGAGTGGTCA CCCACTCCCAGTCCTTCCGGTTCCCGACCTTCAACACCTAAAAGTGATTCAGAATTGGTC AGCAAGTCCACGGAAAGGACAGGGCAGAAGAACCCAGAAATGCTTTGGCTGTGGGGAGAG CTGCCGCAGGCTGCTAAGTCTTCTTCTCCACACAAGATGAAAGAGTCCAGCCCATTGAGC AGTAGAAAAATTTGTGATAAAAGTCACTTTCAGGCCATTCACAGCGAATCTTCAGACACT TTTAGTGACCAATCGCCAACTCTGGTCGGTGGGGCACTTTTGGACCAGAACAAGCCTCAG ACAGAAATGCAGTTTGTGAATGAAGAAGACCTGGAGACCTTAGGAGCAGCAGCGCCACTC TTGCCCATGATCGAGGAGCTCAAACCCCCCTCTGCCAGTGTAGTCCAGACAGCAAACAAG ACGGATTCTCCTTCCAGGAAAAGAGATAAACGAAGCCGACATCTTGGTGCTGACGGCGTC TACTTGGATGACCTCACAGACATGGATCCTGAAGTGGCGGCCCTGTATTTTCCCAAAAAC GGAGATCCTTCCGGACTCGCAAAACATGCAAGCGACAACGGAGCCCGGTCAGCCAACCAG TCCCCGCAGTCGGTGGGCAGCTCGGGCGTGGACAGTGGCGTGGAGAGCACCTCGGACGGG CTGAGGGACCTCCCTTCCATCGCCATCTCCCTCTGCGGGGGCCTCAGCGACCACCGGGAG ATCACGAAAGATGCATTCCTGGAGCAAGCTGTGTCATATCAACAGTTTGTGGACAACCCC GCTATTATCGATGACCCCAATCTCGTGGTAAAGATTGGGAGTAAATATTATAACTGGACA ACAGCAGCACCCCTCCTCCTGGCAATGCAGGCCTTCCAGAAACCTTTGCCAAAGGCCACT GTGGAATCTATCATGAGGGATAAAATGCCCAAAAAGGGAGGAAGATGGTGGTTTTCATGG AGGGGAAGAAACACCACAATCAAGGAGGAAAGTAAGCCAGAGCAGTGCTTGGCTGGCAAG GCCCATAGCACCGGAGAGCAACCGCCGCAGCTCAGCTTGGCCACCAGGGTAAAGCATGAA TCATCCTCCAGTGATGAGGAGCGCGCAGCTGCCAAGCCATCAAACGCAGGCCACCTCCCT CTTCTGCCTAATGTCAGCTACAAGAAGACTCTCCGGCTGACTTCCGAGCAGCTTAAAAGC TTGAAGTTGAAGAATGGCCCCAACGACGTGGTTTTCAGTGTCACCACGCAGTACCAAGGC ACGTGCCGCTGTGAGGGCACCATCTATCTGTGGAACTGGGATGATAAAGTCATCATTTCT GATATTGATGGGACAATTACCAGATCAGATACTCTTGGCCACATTTTGCCCACCCTTGGG AAGGATTGGACCCATCAGGGCATCGCTAAGCTGTACCATAAAGTGAGCCAGAATGGATAT AAATTTCTCTACTGTTCTGCCCGTGCCATCGGGATGGCGGACATGACGCGGGGCTACCTG CACTGGGTCAACGAGAGGGGCACGGTGCTGCCCCAGGGGCCCCTGCTGCTGAGTCCCAGC AGCCTCTTCTCTGCCCTGCACAGAGAAGTGATTGAAAAGAAGCCAGAAAAGTTTAAAGTC CAGTGTTTGACAGACATCAAAAACCTGTTTTTCCCCAACACAGAACCCTTTTATGCTGCT TTTGGAAACCGACCAGCTGATGTGTATTCATACAAGCAAGTAGGAGTGTCTTTGAATAGA ATATTTACCGTCAACCCTAAAGGAGAGCTGGTACAGGAACATGCAAAGACCAACATCTCT TCGTATGTGAGACTCTGTGAAGTAGTCGACCACGTTTTCCCGTTGCTGAAAAGAAGCCAT TCTTCAGACTTTCCCTGTTCGGATACCTTCAGTAACTTCACCTTTTGGAGAGAGCCACTG CCACCTTTTGAAAACCAGGACATTCATTCTGCCTCAGCGTAAAATGTCCCAAGCAGCCTC TTGCCAGCAGTGCAGAGCCTGGTTGTCACCCATTAAAGGATAGGTCTCCCCGGAGTGCAC AGCTCCACCTGGGAGCCTGGCGCGTCATCATTGGCCTGACAGCAGAGAGAATTGAGAAGC ATTTCTCCCCTGCCCCACCCCGGGGCTGACATTTCTAAGCAAGATAGGAAGGGAGCACTT TCTAGGCTAGGAGTTGGGTGCATTTGTACCGTGAAAAGCATTCCTCAGTTGTGGCTTAAT GCCAGTTACGACGCTGCCTTTCCG >OriGene 5' read for NM_145693 unedited
GTTTTTAAATTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCAGCCGGCG GCGGGCTGGGTGTTTGCAATACAAAGGCGGCCACGCGCGGCGCCGCTCGGTGCAGACCAT GAATTACGTGGGGCAGTTAGCCGGCCAGGTGTTTGTCACCGTGAAGGAGCTCTACAAGGG GCTGAATCCCGCCACACTCTCAGGGTGCATTGACATCATTGTCATCCGCCAGCCCAATGG AAACCTCCAATGCTCCCCTTTCCACGTCCGCTTTGGGAAGATGGGGGTCCTGCGCTCCCG AGAGAAAGTGGTTGACATAGAAATCAATGGGGAATCTGTGGATTTGCATATGAAATTGGG AGATAATGGAGAAGCATTTTTTGTTCAAGAAACAGATAATGATCAGGAAGTTATCCCTAT GCACCTGGCCACCTCCCCCATCCTGTCAGAAGGAGCTTCGAGAATGGAATGCCAGCTGAA AAGGGGCTCTGTGGACAGGATGAGAGGCCTGGACCCCAGCACGCCAGCCCAAGTGATCGC TCCCAGCGAGACGCCGTCAAGCAGCTCTGTAGTAAAGAAGAGAAGAAAAAGGAGGAGAAA GTCACAGCTGGACAGCCTGAAGAGAGATGACAACATGAACACATCTGANGATGAGGACAT GTTCCCCATCGAGATGAGCTCGGATGAGGCCATGGAGCTGCTGGAGAGCAGCAGAACTCT TCCTATGATATACCTNCATTCCAGATGATATTCCTGAGGAAAACCTCTCCCTGCTGTGAT TTACCCTCAGTCAGCCTCATACCCTAATTNCGATAGAGAGTGGTCACCCACTCCCAGTNC TTNCGNTTCCGACTTCNACACCTAAAGTGATTCAGAATTGTCAGCAGTCCACGAA >OriGene 3' read for NM_145693 unedited
TGGACCGCGCGCCGTTTTTAGNANCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTGATT TGAGTCTTACTTTGTCACCCAGGCTGGAGTGCAGTAGTGCAAGCTCGGCTCACTGCAACC TCAGGCAGGACTATTTTTAATTATTTTTAATACCTGCAAAAGGGAATCTGCACATGCACA TCCGTGTTTCTACAGAAATCTGCGATCGATGGCAGATCTGTTTGCCTTTGGGTGTCCACA TGAACCATTTGGCAAAGGCATCCAATGCTAACGGGGCCCACCAACTACAACGGAGGCAAC AACTCTGTGGATTTTCTTTCACAGAAAGAGTAAAATTTCATTCAACCGTTCCATTTTTTG CCTCCTGTGATTCTAACAATGAAATTTAAATAGGAAAATGTTTCAATCGTTGGAGTAAAA CACTTTTTAAAAAAATAATGCTTCGAAAAGCAAAGCAAAATCTTTTACCAAAATAATTCT TTCACTTTTCAAATTGCCCTGTCCACGAGCCAGTGTAATAAACAAGTGAAAGAATCACAT TCTGTAGGCTTAAAGAATGCCAAATTATTACTTTTTCGCTTGCCCTTAATTTGAGTGGAA AAAGCTAAGGAACACACATGACTCATAAATTTCCAAAGAATGCCAGTCTATGAGAAAGAC AGAATAAGGCCCTTTCGATAGTCCAACACATACCTCTTTTTAATATATTAATGACAGCGG TATAAAACGAATATGAATAAATGCTTATCCCCGTACCCTAATCCGAGAAAACATTTCCTA CTTTTTAAATAATATAGTGACCTCTTGAAATATTTTCTAAACCAACACCTTCTTTGGAAA CCCCCACAGAGGCAGATCATTACATTTCACATAAGGGCGCCAAGTCCACTGTCGACACAC CTCCCTGAAGATAGAGATCGCCCGCCCACATTTTCAAAACCGCTTTACATATTCTATGCA CTTTACCTAAGCGTCGCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_145693 |
| Insert Size | 4230 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_145693.1, NP_663731.1 |
| RefSeq Size | 5363 bp |
| RefSeq ORF | 2673 bp |
| Locus ID | 23175 |
| UniProt ID | Q14693 |
| Domains | lipin_N |
| Gene Summary | This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017] Transcript Variant: This variant (1) represents the shortest transcript and encodes the shortest isoform (1; also known as alpha). Both variants 1 and 5 encode the same isoform (1). |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Subcellular Localization and Role of Lipin-1 in Human Macrophages
,Martín Valdearcos, Esperanza Esquinas, Clara Meana, Luis Gil-de-Gómez, Carlos Guijas, Jesús Balsinde, and María A. Balboa,
J. Immunol., May 2011; 186: 6004 - 6013
[LPIN1]
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Characterization of the Human LPIN1-encoded Phosphatidate Phosphatase Isoforms
,Gil-Soo Han and George M. Carman,
J. Biol. Chem., May 2010; 285: 14628 - 14638
[LPIN1]
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The Saccharomyces cerevisiae Lipin Homolog Is a Mg2+-dependent Phosphatidate Phosphatase Enzyme
,Gil-Soo Han, Wen-I Wu, and George M. Carman,
J. Biol. Chem. 2006 Apr 7;281(14):9210-8.
[LPIN1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207138 | LPIN1 (Myc-DDK-tagged)-Human lipin 1 (LPIN1) |
CNY 6,520.00 |
|
| RC207138L1 | Lenti-ORF clone of LPIN1 (Myc-DDK-tagged)-Human lipin 1 (LPIN1) |
CNY 8,920.00 |
|
| RC207138L2 | Lenti-ORF clone of LPIN1 (mGFP-tagged)-Human lipin 1 (LPIN1) |
CNY 5,890.00 |
|
| RC207138L3 | Lenti-ORF clone of LPIN1 (Myc-DDK-tagged)-Human lipin 1 (LPIN1) |
CNY 8,920.00 |
|
| RC207138L4 | Lenti-ORF clone of LPIN1 (mGFP-tagged)-Human lipin 1 (LPIN1) |
CNY 5,890.00 |
|
| RG207138 | LPIN1 (tGFP-tagged) - Human lipin 1 (LPIN1) |
CNY 8,120.00 |
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