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ATF1 (NM_005171) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC205923L2V
- LentiORF®
-
Lenti ORF particles, ATF1 (mGFP-tagged) - Human activating transcription factor 1 (ATF1), 200ul, >10^7 TU/mL
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CNY 9,120.00
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Specifications
| Product Data | |
| Product Name | ATF1 (NM_005171) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | EWS-ATF1; FUS/ATF-1; TREB36 |
| Vector | pLenti-C-mGFP |
| ACCN | NM_005171 |
| ORF Size | 813 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC205923).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_005171.2 |
| RefSeq Size | 2505 bp |
| RefSeq ORF | 816 bp |
| Locus ID | 466 |
| Domains | pKID, BRLZ |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 29.2 kDa |
| Gene Summary | This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010] |
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