NEK3 (NM_152720) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205775L1V

  • LentiORF®

Lenti ORF particles, NEK3 (Myc-DDK tagged) - Human NIMA (never in mitosis gene a)-related kinase 3 (NEK3), transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 8,930.00


货期*
详询

规格
    • 200 ul

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Specifications

Product Data
Product Name NEK3 (NM_152720) Human Tagged ORF Clone Lentiviral Particle
Synonyms HSPK36
Vector pLenti-C-Myc-DDK
ACCN NM_152720
ORF Size 1518 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC205775).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_152720.1, NP_689933.1
RefSeq Size 2424 bp
RefSeq ORF 1521 bp
Locus ID 4752
Domains pkinase, TyrKc, S_TKc
Protein Families Druggable Genome, Protein Kinase
MW 57.7 kDa
Gene Summary This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Two functional alleles for this gene have been identified in humans. The reference genome assembly (GRCh38) represents a functional allele that is associated with the inclusion of an additional coding exon in protein-coding transcripts, compared to an alternate functional allele that lacks the exon. [provided by RefSeq, Sep 2019]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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