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RASD2 (NM_014310) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC201454L1V
- LentiORF®
-
Lenti ORF particles, RASD2 (Myc-DDK tagged) - Human RASD family, member 2 (RASD2), 200ul, >10^7 TU/mL
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CNY 8,170.00
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Specifications
| Product Data | |
| Product Name | RASD2 (NM_014310) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | Rhes; TEM2 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_014310 |
| ORF Size | 798 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC201454).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014310.3 |
| RefSeq Size | 3047 bp |
| RefSeq ORF | 801 bp |
| Locus ID | 23551 |
| Domains | ras, RAN, RAS, RHO, RAB |
| Protein Families | Druggable Genome |
| MW | 30.4 kDa |
| Gene Summary | This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016] |
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