Phex (NM_011077) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR227127L4V
- LentiORF®
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Lenti ORF particles, Phex (GFP-tagged) - Mouse phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) (Phex), 200ul, >10^7 TU/mL
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CNY 13,775.00
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Specifications
Product Data | |
Product Name | Phex (NM_011077) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | Gy; HPDR; HPDR1; Hyp; PEX |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_011077 |
ORF Size | 2247 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR227127).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_011077.2, NP_035207.1 |
RefSeq Size | 6265 bp |
RefSeq ORF | 2250 bp |
Locus ID | 18675 |
Gene Summary | Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity (By similarity). Cleaves ASARM peptides between Ser and Glu or Asp residues (By similarity). Regulates osteogenic cell differentiation and bone mineralization through the cleavage of the MEPE-derived ASARM peptide (PubMed:11159866, PubMed:18597632, PubMed:26051469). Promotes dentin mineralization and renal phosphate reabsorption by cleaving DMP1- and MEPE-derived ASARM peptides (PubMed:26051469). Inhibits the cleavage of MEPE by CTSB/cathepsin B thus preventing MEPE degradation (By similarity).[UniProtKB/Swiss-Prot Function] |
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