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Phex (NM_011077) Mouse Untagged Clone
CAT＃: MC221291
Phex (untagged) - Mouse phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) (Phex), (10ug)
CNY 9,690.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Gy; HPDR; HPDR1; Hyp; PEX |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC221291 representing NM_011077
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAAGCAGAAACAGGGAGCACCATGGAGACTGGAAAGGGGACCAACCGAGGCATTCGGATTGCACTGG CCCTGTTTATTGGTGGCACCCTGGTGTTGGGCACACTGCTCTTTCTAGTGAGTCAAGGTCTCCTAAGTTT CCAAGCTAAACAGGAGTACTGTCTGAAGCCAGAATGCATAGAAGCCGCTGCTGCCATCATGAGCAAAGTA AATCTTTCTGTGGATCCTTGTGAGAATTTTTTCCGGTTTGCTTGTGATGGCTGGATAAGCAATAACCCAA TTCCTGAAGATATGCCAAGCTATGGGGTTTATCCTTGGCTGAGACACAATGTTGACCTCAAGTTGAAGGC ACTTCTGGAGAAATCAGTCAGCCGAAGGCGGGACACTGAAGCCGTACAGAAAGCCAAAATCCTCTACTCA TCCTGCATGAATGAGAAAGCAATTGAAAAAGCAGATGCCAAGCCACTGCTCCACATCTTGAGGCATTCAC CTTTCCGCTGGCCAGTGCTTGAAGCTAATATTGGTCCTGAAGGGGTTTGGTCAGAGAGAAAATTCAGTCT ACTGCAAACACTGGCAACGTTCCGCGGTCAATACAGCAATTCTGTGTTCATCCGTTTGTATGTGTCCCCT GATGACAAGGCATCCAATGAACATATCTTGAAGCTGGACCAAGCAACACTCTCTCTGGCTGTAAGGGAAG ACTTCCTGGATAACACTACTGAAGCCAAATCTTATCGGGATGCCCTTTACAAATTCATGGTGGACACTGC TGTGCTTTTAGGAGCTAATAGCTCTCGAGCTGAACATGACATGAAGTCGGTGCTTAGACTGGAAATTAAG ATAGCTGAGATAATGATTCCACATGAGAACCGAACCAGTGAGGCTATGTATAACAAAATGAACATCTCAG AACTCAGCGCTATGATTCCCCAGTTTGACTGGCTGGGCTATATCAAGAAGGTCATTGATACCAGACTCTA CCCACACTTGAAAGACATTGGTCCCTCGGAGAATGTGGTGGTCCGCGTCCCACAGTACTTTAAAGATTTG TTTAGGATATTAGGTGCCGAGAGGAAGAAAACCATTGCCAATTATTTAGTGTGGAGAATGGTTTATTCCA GAATTCCAAACCTCAGCAGGCGCTTTCAATATAGATGGCTAGAATTCTCAAGGGTAATCCAGGGGACCAC AACTCTGCTGCCTCAGTGGGACAAATGTGTCAACTTTATTGAGAGTGCACTCCCATATGTTGTGGGGAAA ATGTTTGTGAATGTTCACTTCCAGGAGGATAAGAAGGAAATGATGGAAGAATTGATTGAGGGTGTTCGCT GGGCCTTCATTGACATGCTGGAGAAAGAAAATGAATGGATGGATGCAGGGACAAAAAGGAAAGCTCAAGA AAAGGCAAGAGCTGTTTTGGCAAAAGTTGGCTATCCAGAGTTTATAATGAATGATACTTATGTTAATGAA GACCTCAAGGCAATCAAATTTTCAGAATCGGACTACTTTGGCAACGTACTGCAAACCCGCAAGTATTTAG CACAGTCTGATTTCTTCTGGCTAAGAAAAGCTGTTCCCAAAACAGAGTGGTTTACAAACCCAACAACAGT CAATGCCTTTTACAGTGCATCTACCAACCAGATACGATTTCCTGCTGGAGAGCTGCAGAAGCCTTTCTTT TGGGGAACAGAATACCCTCGATCCCTGAGTTATGGTGCTATAGGAGTAATTGTGGGCCATGAATTTACAC ATGGATTTGATAATAATGGTAGAAAATATGATAAAAATGGAAACCTTGATCCGTGGTGGTCTGTGGAATC AGAAGAAAAGTTTAAGGAAAAAACAAAATGCATGATTAACCAGTATAGCAACTATTATTGGAAGAAAGCC GGCTTAAATGTGAAAGGGAAGAGGACCCTGGGAGAAAATATTGCTGATAATGGGGGTCTGCGAGAAGCTT TTAGGGCTTACAGGAAATGGATAAATGATAGAAGACAGGGAGTTGAAGAGCCCCTCCTACCAGGCATCAC ATTCACCAACAATCAGCTCTTCTTCCTGAGTTATGCTCATGTAAGGTGCAATTCCTATAGACCAGAAGCT GCCAGAGAACAAGTGCAAATTGGTGCTCACAGTCCTCCACAATTTAGGGTCAATGGTGCCATTAGCAACT TTGAAGAATTTCAGAAAGCTTTTAACTGTCCACGAAATTCCACTATGAACAGAGGTGCAGATTCCTGCCG ACTCTGGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_011077 |
| Insert Size | 2250 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_011077.2, NP_035207.1 |
| RefSeq Size | 6265 bp |
| RefSeq ORF | 2250 bp |
| Locus ID | 18675 |
| UniProt ID | P70669 |
| Gene Summary | Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity (By similarity). Cleaves ASARM peptides between Ser and Glu or Asp residues (By similarity). Regulates osteogenic cell differentiation and bone mineralization through the cleavage of the MEPE-derived ASARM peptide (PubMed:11159866, PubMed:18597632, PubMed:26051469). Promotes dentin mineralization and renal phosphate reabsorption by cleaving DMP1- and MEPE-derived ASARM peptides (PubMed:26051469). Inhibits the cleavage of MEPE by CTSB/cathepsin B thus preventing MEPE degradation (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227127 | Phex (tGFP-tagged) - Mouse phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia vitamin D resistant rickets) (Phex), (10ug) |
CNY 6,370.00 |
|
| MR227127 | Phex (Myc-DDK-tagged) - Mouse phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) (Phex) |
CNY 5,488.00 |
|
| MR227127L3 | Lenti ORF clone of Phex (Myc-DDK-tagged) - Mouse phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) (Phex) |
CNY 7,700.00 |
|
| MR227127L4 | Lenti ORF clone of Phex (mGFP-tagged) - Mouse phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) (Phex) |
CNY 7,700.00 |
