Upf2 (NM_001081132) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR226926L4V
- LentiORF®
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Lenti ORF particles, Upf2 (GFP-tagged) - Mouse UPF2 regulator of nonsense transcripts homolog (yeast) (Upf2), 200ul, >10^7 TU/mL. Note: ORF is codon optimized
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CNY 20,235.00
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Specifications
Product Data | |
Product Name | Upf2 (NM_001081132) Mouse Tagged ORF Clone Lentiviral Particle |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001081132 |
ORF Size | 3807 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR226926).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001081132.1, NP_001074601.1 |
RefSeq Size | 5174 bp |
RefSeq ORF | 3810 bp |
Locus ID | 326622 |
Gene Summary | Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA.[UniProtKB/Swiss-Prot Function] |
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