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Upf2 (NM_001081132) Mouse Untagged Clone
CAT＃: MC224119
Upf2 (untagged) - Mouse UPF2 regulator of nonsense transcripts homolog (yeast) (Upf2), (10ug)
CNY 16,340.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224119 representing NM_001081132
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCAGCTGAGCGTAAAAAGTCAGCAAGTATGGAAGAAAAAGAATCTTTACTAAACAACAAGGAAAAAG ACTGCAGTGAGAGGCGGCCAGTGAGCAGCAAGGAGAAACCAAGGGACGACCTCAAGGTCACTGCCAAGAA GGAGGTCAGTAAGGTCCCAGAAGACAAAAAGAAGAGACTGGAAGAAGATAAGAGAAAAAAGGAAGACAAG GAACGCAAGAAAAAAGAGGAAGAGAAGGTGAAGGCAGAGGAAGAGTTAAAGAAGAAGGAAGAGGAAGAAA AGAAGAAACAGGAAGAGGAAGAGAGGAAAAAGCAGGAGGAGCAGGCCAAGCGGCAGCAGGAAGAAGCGGC TGCTCAGCTGAAAGAGAAAGAAGAATCTCTTCAGCTTCATCAGGAGGCCTGGGAACGCCATCAATTACGA AAGGAACTTCGTAGCAAAAACCAAAATGCTCCAGACAACCGACCAGAGGAAAATTTCTTTAGCCGCCTAG ATTCGAGCTTAAAGAAAAATACCGCTTTTGTCAAGAAACTAAAAACAATTACAGAACAACAGAGAGACTC CTTGTCTCATGATTTTAATGGCCTGAATTTAAGCAAATATATTGCAGAAGCCGTAGCTTCCATTGTGGAG GCAAAATTAAAACTCTCTGACGTGAACTGTGCTGCGCACCTCTGCTCTCTCTTTCACCAGCGGTACTCTG ACTTTGCGCCCTCTCTTCTTCAGGTGTGGAAAAAACATTTCGAAGCGAGGAAAGAGGAGAAAACGCCTAA CATTACCAAGCTAAGAACTGACTTGCGTTTCATTGCAGAATTGACAATAGTGGGAATTTTCACTGACAAG GAAGGTCTTTCCTTAATCTACGAACAGCTAAAAAGTATTATTAATGCTGATCGAGAATCCCACACTCATG TTTCTGTGGTGATTAGTTTCTGTCGCCATTGTGGAGATGACATTGCTGGACTTGTACCGAGGAAAGTAAA AAGTGCTGCGGAGAAGTTTAATTTGAGTTTTCCTCCTAGTGAGATCATTAGTCCGGAGAAGCAGCAGCCT TTCCAGAATCTTTTAAAAGAGTACTTTACGTCTTTGACCAAACACCTGAAAAGGGACCACAGGGAGCTGC AGAACACTGAGAGGCAAAACAGGCGTATTCTGCACTCTAAAGGCGAGCTAAGTGAGGACAGGCACAAGCA ATATGAGGAGTTTGCAATGTCTTACCAGAAGCTGCTGGCGAACTCTCAGTCCTTAGCGGACCTTTTGGAT GAAAATATGCCCGATCTTCCTCAGGACAAACCCACACCAGAAGAGCATGGGCCCGGAATCGACATATTTA CACCCGGCAAACCTGGAGAGTATGACTTAGAAGGTGGCATTTGGGAAGATGAAGACGCTCGGAATTTTTA TGAAAACCTCATCGATTTGAAAGCATTTGTTCCAGCCATCTTGTTCAAAGACAATGAAAAAAGTCAGAAC AAAGATTCTAACAAAGATGATTCCAAAGAGGCAAAAGAACCAAAGGATAATAAGGAGGCATCAAGTCCTG ATGATTTGGAACTTGAGTTGGAGAATTTAGAAATTAATGATGATACATTGGAGTTAGAAGGTGCAGATGA AGCTGAAGATCTTACAAAGAAACTTCTTGATGAACAAGAACAAGAAGATGAAGAAGCCAGCACTGGATCT CATCTCAAACTCATAGTAGATGCTTTCCTCCAGCAGCTGCCCAACTGTGTCAACCGAGACCTAATCGACA AGGCAGCCATGGATTTTTGCATGAACATGAACACAAAGGCAAACAGGAAGAAGTTGGTGCGGGCACTCTT CATAGTTCCTAGGCAGAGGTTGGATTTGCTACCATTTTATGCAAGATTGGTTGCTACCTTGCACCCCTGC ATGTCTGATGTAGCAGAGGATCTTTGTTCCATGCTGAGGGGGGATTTCAGATTTCATGTTCGAAAAAAGG ACCAGATCAACATTGAAACAAAGAACAAAACTGTCCGCTTTATTGGAGAGCTAACCAAGTTTAAGATGTT CACCAAAAATGATACACTGCATTGTCTAAAGATGCTTCTGTCAGATTTCTCTCATCATCATATTGAAATG GCATGCACTCTACTGGAGACCTGCGGAAGATTTCTCTTCAGATCTCCAGAATCACACCTGAGGACCAGTG TGCTTTTGGAGCAAATGATGAGAAAGAAACAAGCAATGCATCTTGATGCACGATATGTTACAATGGTAGA AAATGCATATTATTACTGCAACCCACCGCCCGCCGAAAAGACCGTGAGAAAGAAACGCCCTCCTCTTCAG GAGTATGTCCGCAAGCTTCTGTACAAGGATCTCTCTAAGGTCACGACGGAAAAGGTTTTGAGACAGATGC GAAAGTTGCCCTGGCAGGACCAAGAAGTAAAAGACTATGTTATTTGTTGTATGATAAACATCTGGAACGT GAAATACAACAGTATTCACTGTGTAGCCAACCTCCTAGCAGGGCTAGTTCTCTACCAGGAGGATGTTGGG ATCCATGTTGTGGATGGCGTACTCGAAGATATTCGATTGGGAATGGAGGTTAATCAACCTAAATTTAACC AGAGGCGTATCAGTAGTGCCAAGTTCTTAGGAGAACTTTATAATTACAGAATGGTCGAATCAGCTGTTAT TTTCAGAACTCTTTATTCTTTTACTTCATTTGGTGTCAACCCTGATGGGTCTCCAAGTTCCCTGGACCCT CCTGAGCATCTCTTTAGAATTAGACTAGTATGCACTATTTTGGATACCTGTGGCCAGTACTTTGACAGAG GTTCCAGTAAACGAAAACTTGACTGCTTCCTTGTATATTTTCAGCGTTATGTTTGGTGGAAGAAAAGTTT GGAGGTTTGGACAAAAGACCATCCATTTCCTATTGATATAGATTACATGATCAGTGATACACTAGAACTG CTAAGACCAAAGATCAAACTCTGTAATTCTCTGGAAGAATCCATCAGGCAGGTACAAGACTTGGAACGAG AATTCTTAATAAAACTAGGCCTAGTAAATGACAAAGAGTCCAAAGATTCTATGACAGAAGGGGAAAATCT TGAAGAGGATGAAGAAGAAGAAGAAGGAGGAGCTGAGACAGAGGAACAGTCTGGAAATGAAAGTGAAGTG AACGAGCCAGAAGAAGAAGAGGGTTCTGAGGAGGAGGAGGAGGGAGAGGAGGAGGAAGAGGAGAATACAG ATTACCTCACAGATTCCAACAAGGAGAACGAGACTGATGAAGAAAATGCTGAGGTGATGATTAAGGGAGG CGGACTGAAGCATGTTCCTTGTGTAGAAGATGAGGACTTCATTCAAGCTCTGGACAAAATGATGCTAGAA AACCTTCAGCAGCGAAGTGGTGAGTCTGTTAAAGTGCACCAGCTTGATGTTGCTATCCCTTTGCATCTCA AAAGCCAGCTGAGGAAAGGGCCCCCGCTTGGCGGTGGGGAAGGAGAGACGGAGTCTGCAGACACGATGCC ATTTGTCATGTTAACAAGAAAAGGCAATAAACAGCAGTTTAAGATTCTCAATGTGCCCATGTCATCCCAA CTTGCTGCAAATCATTGGAACCAGCAACAAGCAGAACAAGAGGAGAGGATGAGGATGAAAAAGCTCACCT TAGACATCAATGAACGACAAGAGCAAGAAGATTATCAAGAAATGTTGCAGTCTCTTGCACAGCGCCCAGC TCCAGCAAACACTAATCGTGAGCGGCGGCCTCGTTACCAGCATCCAAAGGGAGCACCTAATGCAGATCTA ATCTTTAAGACTGGTGGGAGGAGACGTTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001081132 |
| Insert Size | 3810 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001081132.1, NP_001074601.1 |
| RefSeq Size | 5174 bp |
| RefSeq ORF | 3810 bp |
| Locus ID | 326622 |
| UniProt ID | A2AT37 |
| Gene Summary | Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226926 | Upf2 (tGFP-tagged) - Mouse UPF2 regulator of nonsense transcripts homolog (yeast) (Upf2), (10ug). Note: ORF is codon optimized |
CNY 13,870.00 |
|
| MR226926 | Upf2 (Myc-DDK-tagged) - Mouse UPF2 regulator of nonsense transcripts homolog (yeast) (Upf2). Note: ORF is codon optimized |
CNY 8,840.00 |
|
| MR226926L3 | Lenti ORF clone of Upf2 (Myc-DDK-tagged) - Mouse UPF2 regulator of nonsense transcripts homolog (yeast) (Upf2). Note: ORF is codon optimized |
CNY 14,540.00 |
|
| MR226926L4 | Lenti ORF clone of Upf2 (mGFP-tagged) - Mouse UPF2 regulator of nonsense transcripts homolog (yeast) (Upf2). Note: ORF is codon optimized |
CNY 14,540.00 |
