Pcdh8 (NM_001042726) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR225812L3V
- LentiORF®
-
Lenti ORF particles, Pcdh8 (Myc-DDK-tagged) - Mouse protocadherin 8 (Pcdh8), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 14,915.00
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Specifications
Product Data | |
Product Name | Pcdh8 (NM_001042726) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 1700080P15Rik; P; Papc |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001042726 |
ORF Size | 2919 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR225812).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001042726.3, NP_001036191.1 |
RefSeq Size | 3725 bp |
RefSeq ORF | 2922 bp |
Locus ID | 18530 |
Gene Summary | This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a type I transmembrane protein composed of an extracellular domain including 6 cadherin ectodomains, a single-pass transmembrane domain and a cytoplasmic tail. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons with the first large exon encoding the extracellular and transmembrane region. Although this gene product is capable of homophilic interaction, it appears to affect cell-cell adhesion indirectly by initiating signaling events that regulate classical cadherin-mediated adhesion. Based on studies on this protein and its orthologs, this protocadherin mainly functions in developing embryos and the central nervous system, but can also function as a tumor suppressor. Alternative splicing yielding isoforms with unique cytoplasmic tails has been reported. [provided by RefSeq, Sep 2009] |
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