Neurod2 (NM_010895) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR225256L2V
- LentiORF®
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Lenti ORF particles, Neurod2 (GFP-tagged) - Mouse neurogenic differentiation 2 (Neurod2), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | Neurod2 (NM_010895) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | bHLHa1; Ndrf |
Vector | pLenti-C-mGFP |
ACCN | NM_010895 |
ORF Size | 1149 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR225256).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_010895.3, NP_035025.3 |
RefSeq Size | 3137 bp |
RefSeq ORF | 1152 bp |
Locus ID | 18013 |
Gene Summary | Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter.[UniProtKB/Swiss-Prot Function] |
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