Erap1 (NM_030711) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR224333L2V
- LentiORF®
Lenti ORF particles, Erap1 (GFP-tagged) - Mouse endoplasmic reticulum aminopeptidase 1 (Erap1), 200ul, >10^7 TU/mL
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CNY 16,055.00
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Specifications
Product Data | |
Product Name | Erap1 (NM_030711) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | Arts1; ERAAP; PILSA; PILSAP |
Vector | pLenti-C-mGFP |
ACCN | NM_030711 |
ORF Size | 2790 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR224333).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_030711.4 |
RefSeq Size | 4014 bp |
RefSeq ORF | 2793 bp |
Locus ID | 80898 |
Gene Summary | Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney (By similarity).[UniProtKB/Swiss-Prot Function] |
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