Kdm5d (NM_011419) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR223231L4V
- LentiORF®
Lenti ORF particles, Kdm5d (GFP-tagged) - Mouse lysine (K)-specific demethylase 5D (Kdm5d), 200ul, >10^7 TU/mL
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CNY 23,750.00
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Specifications
Product Data | |
Product Name | Kdm5d (NM_011419) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | HY; Jarid1d; Smcy |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_011419 |
ORF Size | 4644 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR223231).
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OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_011419.3, NP_035549.1 |
RefSeq Size | 5471 bp |
RefSeq ORF | 4647 bp |
Locus ID | 20592 |
Gene Summary | Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes; in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity by demethylating H3K4me3 active transcription marks (By similarity).[UniProtKB/Swiss-Prot Function] |
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