United States
Germany
Japan
United Kingdom
China
Ehmt2 (NM_145830) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR222714L4V
- LentiORF®
-
Lenti ORF particles, Ehmt2 (GFP-tagged) - Mouse euchromatic histone lysine N-methyltransferase 2 (Ehmt2), transcript variant long, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 20,235.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Ehmt2 (NM_145830) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Bat8; D17Ertd710e; G9a; KMT1C; NG36 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_145830 |
| ORF Size | 3792 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR222714).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_145830.1 |
| RefSeq Size | 4070 bp |
| RefSeq ORF | 3792 bp |
| Locus ID | 110147 |
| Gene Summary | Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. May also methylate histone H1. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53. Also methylates CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6, KLF12 and itself.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
