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Derl3 (NM_024440) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR222306L3V
- LentiORF®
-
Lenti ORF particles, Derl3 (Myc-DDK-tagged) - Mouse Der1-like domain family, member 3 (Derl3), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Derl3 (NM_024440) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1810006I20Rik; 1810063P04Rik; derlin-3; IZP6 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_024440 |
| ORF Size | 687 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR222306).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_024440.2, NP_077760.1 |
| RefSeq Size | 1336 bp |
| RefSeq ORF | 687 bp |
| Locus ID | 70377 |
| Gene Summary | Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the misfolded glycoproteins. May be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation.[UniProtKB/Swiss-Prot Function] |
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