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Uvssa (NM_001081101) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR218039L3V
- LentiORF®
-
Lenti ORF particles, Uvssa (Myc-DDK-tagged) - Mouse RIKEN cDNA 4933407H18 gene (4933407H18Rik), 200ul, >10^7 TU/mL
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CNY 11,970.00
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Specifications
| Product Data | |
| Product Name | Uvssa (NM_001081101) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 4933407H18Rik; D330017J19Rik; Kiaa1530; mKIAA1530 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001081101 |
| ORF Size | 2154 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR218039).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001081101.2, NP_001074570.1 |
| RefSeq Size | 7343 bp |
| RefSeq ORF | 2154 bp |
| Locus ID | 71101 |
| Gene Summary | Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage (By similarity).[UniProtKB/Swiss-Prot Function] |
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