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Cand1 (NM_027994) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR216867L3V
- LentiORF®
-
Lenti ORF particles, Cand1 (Myc-DDK-tagged) - Mouse cullin associated and neddylation disassociated 1 (Cand1), 200ul, >10^7 TU/mL
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CNY 17,860.00
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Specifications
| Product Data | |
| Product Name | Cand1 (NM_027994) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2310038O07Rik; 6330512O03Rik; AI195005; AI846556; D10Ertd516e; mKIAA0829; Tp120a |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_027994 |
| ORF Size | 3690 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR216867).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_027994.1, NP_082270.1 |
| RefSeq Size | 8209 bp |
| RefSeq ORF | 3693 bp |
| Locus ID | 71902 |
| Gene Summary | Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. The exchange activity of CAND1 is coupled with cycles of neddylation conjugation: in the deneddylated state, cullin-binding CAND1 binds CUL1-RBX1, increasing dissociation of the SCF complex and promoting exchange of the F-box protein. Probably plays a similar role in other cullin-RING E3 ubiquitin ligase complexes (By similarity).[UniProtKB/Swiss-Prot Function] |
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