Rab43 (NM_001039394) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR216803L3V
- LentiORF®
Lenti ORF particles, Rab43 (Myc-DDK-tagged) - Mouse RAB43, member RAS oncogene family (Rab43), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Rab43 (NM_001039394) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 1810048P08Rik; 2500004H21Rik; AW490415 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001039394 |
ORF Size | 630 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR216803).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001039394.1, NP_001034483.1 |
RefSeq Size | 4605 bp |
RefSeq ORF | 633 bp |
Locus ID | 69834 |
Gene Summary | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium.[UniProtKB/Swiss-Prot Function] |
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