Topbp1 (NM_176979) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR212017L4V

  • LentiORF®

Lenti ORF particles, Topbp1 (GFP-tagged) - Mouse topoisomerase (DNA) II binding protein 1 (Topbp1), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 23,370.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Topbp1 (NM_176979) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 1110031N14Rik; 2810429C13Rik; AI256758; D430026L04Rik; mKIAA0259
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_176979
ORF Size 4545 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR212017).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_176979.5, NP_795953.2
RefSeq Size 5112 bp
RefSeq ORF 4548 bp
Locus ID 235559
Gene Summary Required for DNA replication (By similarity). Plays a role in the rescue of stalled replication forks and checkpoint control (PubMed:14718568). Binds double-stranded DNA breaks and nicks as well as single-stranded DNA (By similarity). Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage (By similarity). Induces a large increase in the kinase activity of ATR (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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