Mink1 (BC052474) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR211931L4V
- LentiORF®
Lenti ORF particles, Mink1 (GFP-tagged) - Mouse misshapen-like kinase 1 (zebrafish) (cDNA clone MGC:63403 IMAGE:6833893), 200ul, >10^7 TU/mL
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CNY 23,180.00
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Specifications
Product Data | |
Product Name | Mink1 (BC052474) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | B55, MINK, RP23-122P1.6 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | BC052474 |
ORF Size | 4002 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR211931).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | BC052474, AAH52474 |
RefSeq Size | 4842 bp |
RefSeq ORF | 4004 bp |
Locus ID | 50932 |
Gene Summary | Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.[UniProtKB/Swiss-Prot Function] |
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