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Megf10 (NM_001001979) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR211707L3V
- LentiORF®
-
Lenti ORF particles, Megf10 (Myc-DDK-tagged) - Mouse multiple EGF-like-domains 10 (Megf10), 200ul, >10^7 TU/mL
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CNY 16,910.00
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Specifications
| Product Data | |
| Product Name | Megf10 (NM_001001979) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 3000002B06Rik; Gm331 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001001979 |
| ORF Size | 3444 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR211707).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001001979.1, NP_001001979.1 |
| RefSeq Size | 7514 bp |
| RefSeq ORF | 3444 bp |
| Locus ID | 70417 |
| Gene Summary | Membrane receptor involved in phagocytosis by macrophages and astrocytes of apoptotic cells. Receptor for C1q, an eat-me signal, that binds phosphatidylserine expressed on the surface of apoptotic cells (PubMed:27170117). Cooperates with ABCA1 within the process of engulfment (By similarity). Promotes the formation of large intracellular vacuoles and may be responsible for the uptake of amyloid-beta peptides (PubMed:20828568). Necessary for astrocyte-dependent apoptotic neuron clearance in the developing cerebellum (PubMed:27170117). Plays role in muscle cell proliferation, adhesion and motility. Is also an essential factor in the regulation of myogenesis. Controls the balance between skeletal muscle satellite cells proliferation and differentiation through regulation of the notch signaling pathway (PubMed:28498977). May also function in the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (PubMed:22407321).[UniProtKB/Swiss-Prot Function] |
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