United States
Germany
Japan
United Kingdom
China
Ipo5 (NM_023579) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR211627L3V
- LentiORF®
-
Lenti ORF particles, Ipo5 (Myc-DDK-tagged) - Mouse importin 5 (Ipo5), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 16,340.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Ipo5 (NM_023579) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1110011C18Rik; 5730478E03Rik; AA409333; C76941; IMB3; Kpnb3; Ranbp5 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_023579 |
| ORF Size | 3291 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR211627).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_023579.4, NP_076068.1 |
| RefSeq Size | 4598 bp |
| RefSeq ORF | 3294 bp |
| Locus ID | 70572 |
| Gene Summary | Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. Binds to CPEB3 and mediates its nuclear import following neuronal stimulation (PubMed:22730302).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
