Ube2o (BC059193) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR211566L3V

  • LentiORF®

Lenti ORF particles, Ube2o (Myc-DDK-tagged) - Mouse ubiquitin-conjugating enzyme E2O (cDNA clone MGC:65407 IMAGE:4160667), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 15,200.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Ube2o (BC059193) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms E2-230K, mKIAA1734, 9630022H21
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN BC059193
ORF Size 3186 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR211566).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq BC059193.1
RefSeq Size 4569 bp
RefSeq ORF 3188 bp
Locus ID 217342
Gene Summary E2/E3 hybrid ubiquitin-protein ligase that displays both E2 and E3 ligase activities and mediates monoubiquitination of target proteins. Negatively regulates TRAF6-mediated NF-kappa-B activation independently of its E2 activity. Acts as a positive regulator of BMP7 signaling by mediating monoubiquitination of SMAD6, thereby regulating adipogenesis. Mediates monoubiquitination at different sites of the nuclear localization signal (NLS) of BAP1, leading to cytoplasmic retention of BAP1. Also able to monoubiquitinate the NLS of other chromatin-associated proteins, such as INO80 and CXXC1, affecting their subcellular location. Acts as a regulator of retrograde transport by assisting the TRIM27:MAGEL2 E3 ubiquitin ligase complex to mediate 'Lys-63'-linked ubiquitination of WASHC1, leading to promote endosomal F-actin assembly.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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