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Nrp1 (NM_008737) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR211197L4V
- LentiORF®
-
Lenti ORF particles, Nrp1 (GFP-tagged) - Mouse neuropilin 1 (Nrp1), 200ul, >10^7 TU/mL
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CNY 15,960.00
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Specifications
| Product Data | |
| Product Name | Nrp1 (NM_008737) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | C530029I03; NP-1; NPN-1; Npn1; Nrp |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_008737 |
| ORF Size | 2769 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR211197).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_008737.1, NP_032763.2 |
| RefSeq Size | 5921 bp |
| RefSeq ORF | 2772 bp |
| Locus ID | 18186 |
| Gene Summary | Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis (By similarity). Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (PubMed:26503042).[UniProtKB/Swiss-Prot Function] |
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