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Sort1 (NM_019972) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210834L3V
- LentiORF®
-
Lenti ORF particles, Sort1 (Myc-DDK-tagged) - Mouse sortilin 1 (Sort1), 200ul, >10^7 TU/mL
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CNY 13,205.00
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Specifications
| Product Data | |
| Product Name | Sort1 (NM_019972) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2900053A11Rik; AI852375; Ntr3; Ntsr3 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_019972 |
| ORF Size | 2475 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210834).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_019972.2, NP_064356.2 |
| RefSeq Size | 6851 bp |
| RefSeq ORF | 2478 bp |
| Locus ID | 20661 |
| Gene Summary | Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.[UniProtKB/Swiss-Prot Function] |
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