Usp16 (NM_024258) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR210833L4V

  • LentiORF®

Lenti ORF particles, Usp16 (GFP-tagged) - Mouse ubiquitin specific peptidase 16 (Usp16), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 14,725.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Usp16 (NM_024258) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 1200004E02Rik; 2810483I07Rik; 6330514E22Rik; UBPM
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_024258
ORF Size 2478 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR210833).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_024258.1, NP_077220.1
RefSeq Size 2926 bp
RefSeq ORF 2478 bp
Locus ID 74112
Gene Summary Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes (PubMed:24034696). Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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