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Large1 (NM_010687) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210487L3V
- LentiORF®
-
Lenti ORF particles, Large (Myc-DDK-tagged) - Mouse like-glycosyltransferase (Large), 200ul, >10^7 TU/mL
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CNY 12,445.00
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Specifications
| Product Data | |
| Product Name | Large1 (NM_010687) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | BPFD#36; enr; fg; froggy; Gyltl1a; Large; Mbp-1; Mbp1; myd |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_010687 |
| ORF Size | 2268 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210487).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_010687.1, NP_034817.1 |
| RefSeq Size | 3669 bp |
| RefSeq ORF | 2271 bp |
| Locus ID | 16795 |
| Gene Summary | Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:23125099, PubMed:23135544). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration (PubMed:15184894, PubMed:24132234). LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide (By similarity).[UniProtKB/Swiss-Prot Function] |
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