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Crtc1 (NM_001004062) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR209600L4V
- LentiORF®
-
Lenti ORF particles, Crtc1 (GFP-tagged) - Mouse CREB regulated transcription coactivator 1 (Crtc1), 200ul, >10^7 TU/mL
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CNY 12,255.00
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Specifications
| Product Data | |
| Product Name | Crtc1 (NM_001004062) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AI413414; Mect1; mKIAA0616; R74955; TORC1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001004062 |
| ORF Size | 1893 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR209600).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001004062.2, NP_001004062.1 |
| RefSeq Size | 5674 bp |
| RefSeq ORF | 1893 bp |
| Locus ID | 382056 |
| Gene Summary | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites (PubMed:29211348). Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated (PubMed:29211348). Acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells (By similarity). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.[UniProtKB/Swiss-Prot Function] |
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