Crtc1 (NM_001004062) Mouse Untagged Clone
CAT#: MC219955
Crtc1 (untagged) - Mouse CREB regulated transcription coactivator 1 (Crtc1), (10ug)
CNY 8,080.00
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Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | AI413414; Mect1; mKIAA0616; R74955; TORC1 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC219955 representing NM_001004062
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGACTTCGAACAATCCGCGGAAATTTAGCGAGAAGATCGCACTGCACAACCAGAAGCAGGCGGAGG AGACGGCGGCCTTCGAGGAGGTCATGAAGGACCTGAGCCTGACGCGGGCCGCGCGGCTTCAGCTGCAGAA GTCCCAGTACCTGCAGCTGGGCCCCAGCCGTGGCCAGTACTACGGTGGGTCCCTGCCCAACGTGAACCAG ATTGGAAGCAGCAGCGTGGACCTGGCCTTCCAGACCCCATTTCAGTCCTCAGGCCTGGACACGAGTCGGA CCACACGACATCATGGGCTTGTGGACAGAGTATATCGTGAGCGTGGCAGACTTGGCTCCCCGCACCGTCG ACCCCTGTCAGTAGACAAGCATGGGCGACAGGCTGACAGCTGCCCCTATGGCACCGTGTACCTCTCGCCT CCTGCGGACACCAGCTGGAGGAGGACCAACTCTGACTCTGCCCTGCACCAGAGCACAATGACACCCAGCC AGGCAGAGTCCTTCACAGGCGGGTCCCAGGATGCGCACCAGAAGAGAGTCTTACTGCTAACTGTCCCAGG AATGGAGGACACCGGGGCTGAGACAGACAAGACCCTTTCTAAGCAGTCATGGGACTCAAAGAAGGCGGGT TCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTTCCGTCTGCAGACCAGGAGAACACAACAG CCCTGATCCCTGCCACCCACAACACAGGGGGCTCCCTTCCTGACCTCACCAACATCCACTTCCCCTCCCC ACTCCCGACACCACTGGACCCTGAGGAGCCTCCGTTCCCTGCTCTCACCAGCTCCAGCAGCACCGGCAGC CTTGCACATCTGGGCGTTGGCGGCGCAGGCCAGGGTATGAACACCCCCAGCTCTTCTCCACAGCACCGGC CAGCAGTCGTCAGCCCCCTGTCCCTGAGCACAGAGGCCAGGCGGCAGCAGGCCCAGCAGGTGTCACCCAC CCTGTCTCCGTTGTCACCCATCACTCAGGCCGTGGCTATGGATGCCCTGTCCTTGGAGCAGCAGCTGCCC TATGCCTTCTTCACCCAGACTGGCTCCCAGCAGCCTCCCCCACAGCCCCAGCCACCGCCTCCACCTCCAC CGGTATCCCAGCAGCAGCCACCACCTCCACAGGTGTCTGTGGGCCTCCCCCAGGGTGGTCCACTGCTGCC CAGTGCCAGCCTGACTCGGGGGCCCCAGCTGCCACCACTCTCAGTTACTGTACCATCCACTCTTCCCCAG TCCCCTACAGAGAACCCAGGCCAGTCACCAATGGGGATCGATGCCACTTCGGCACCAGCTCTGCAGTACC GCACGAGTGCAGGGTCACCTGCCACCCAGTCTCCCACCTCTCCGGTCTCCAACCAAGGCTTCTCCCCTGG AAGCTCCCCACAGCACACGTCCACCCTGGGCAGCGTGTTTGGGGATGCGTACTATGAGCAGCAGATGACA GCCAGGCAGGCCAATGCTCTGTCCCGCCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCA GCAGCCTATACAACCCGGGCTCCACACTCAACTATTCCCAGGCTGCCATGATGGGTCTGAGCGGGAGCCA CGGGGGCCTACAGGACCCGCAGCAGCTCGGCTACACAGGCCACGGTGGAATCCCCAACATCATCCTCACG GTGACAGGAGAGTCACCACCGAGCCTCTCTAAGGAACTGAGCAGCACACTGGCAGGAGTCAGTGATGTCA GCTTTGATTCAGACCATCAGTTTCCACTGGACGAGCTGAAGATTGACCCTCTGACCCTGGACGGACTCCA TATGTTGAATGACCCAGACATGGTTTTAGCCGACCCAGCCACCGAGGACACCTTCCGAATGGACCGCCTG TGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001004062 |
Insert Size | 1893 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001004062.2, NP_001004062.1 |
RefSeq Size | 5674 bp |
RefSeq ORF | 1893 bp |
Locus ID | 382056 |
UniProt ID | Q68ED7 |
Gene Summary | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites (PubMed:29211348). Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated (PubMed:29211348). Acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells (By similarity). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.[UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG209600 | Crtc1 (tGFP-tagged) - Mouse CREB regulated transcription coactivator 1 (Crtc1) |
CNY 6,080.00 |
|
MR209600 | Crtc1 (Myc-DDK-tagged) - Mouse CREB regulated transcription coactivator 1 (Crtc1) |
CNY 4,696.00 |
|
MR209600L3 | Lenti ORF clone of Crtc1 (Myc-DDK-tagged) - Mouse CREB regulated transcription coactivator 1 (Crtc1) |
CNY 7,410.00 |
|
MR209600L4 | Lenti ORF clone of Crtc1 (mGFP-tagged) - Mouse CREB regulated transcription coactivator 1 (Crtc1) |
CNY 7,410.00 |