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Mbd1 (NM_013594) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR209180L4V
- LentiORF®
-
Lenti ORF particles, Mbd1 (GFP-tagged) - Mouse methyl-CpG binding domain protein 1 (Mbd1), 200ul, >10^7 TU/mL
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CNY 11,780.00
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Specifications
| Product Data | |
| Product Name | Mbd1 (NM_013594) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Cxxc3; PCM1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_013594 |
| ORF Size | 1764 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR209180).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_013594.2 |
| RefSeq Size | 2672 bp |
| RefSeq ORF | 1767 bp |
| Locus ID | 17190 |
| Gene Summary | Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS). Acts as transcriptional repressor and plays a role in gene silencing by recruiting AFT7IP, which in turn recruits factors such as the histone methyltransferase SETDB1. Probably forms a complex with SETDB1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Isoform 1 can also repress transcription from unmethylated promoters.[UniProtKB/Swiss-Prot Function] |
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