Pink1 (NM_026880) Mouse Tagged ORF Clone Lentiviral Particle

CAT＃: MR209092L2V

LentiORF^®

Lenti ORF particles, Pink1 (GFP-tagged) - Mouse PTEN induced putative kinase 1 (Pink1), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

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CNY 11,685.00

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Specifications

Product Data
Product Name	Pink1 (NM_026880) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms	1190006F07Rik; AU042772; AW557854; BRPK; mFLJ00387
Vector	pLenti-C-mGFP
ACCN	NM_026880
ORF Size	1740 bp
Sequence Data	ORF Nucleotide Sequence (showhide) The ORF insert of this clone is exactly the same as(MR209092).
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq	NM_026880.2, NP_081156.2
RefSeq Size	2367 bp
RefSeq ORF	1743 bp
Locus ID	68943
Gene Summary	Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins (PubMed:24652937). Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PRKN (PubMed:24784582). Targets PRKN to dysfunctional depolarized mitochondria through the phosphorylation of MFN2 (By similarity). Activates PRKN in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PRKN and (2) mediating phosphorylation of ubiquitin, converting PRKN to its fully-active form (PubMed:24784582). Required for ubiquinone reduction by mitochondrial complex I by mediating phosphorylation of complex I subunit NDUFA10 (PubMed:24652937).[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Product Manuals
TrueORFs: Open Reading Frame Clones - 10 ug in PrecisionShuttle Vector System pLenti-ORF destination vector Transfection - TurboFectin 8.0 Transfection Reagent Plasmid Preparation - PowerPrep Plasmid Purification Kits
FAQs
TrueORF Clones/PrecisionShuttle Organelle Marker Transfection Reagent
SDS
Lenti SDS

Resources

cDNA 克隆相关资源
Video Tutorial: Clone Selection Guide Product Video: What is TrueORF GOLD and why it is the most popular type of clone Video Tutorial: How to make Lentivirus particles Video Tutorial: Is the Lentivirus Safe Product Brochure: cDNA clones $98 Clones. Download the List of 15,000 Protocol: Lentivirus packaging

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