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Traf3ip2 (NM_134000) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR208800L3V
- LentiORF®
-
Lenti ORF particles, Traf3ip2 (Myc-DDK-tagged) - Mouse TRAF3 interacting protein 2 (Traf3ip2), 200ul, >10^7 TU/mL
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CNY 10,165.00
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规格
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Specifications
| Product Data | |
| Product Name | Traf3ip2 (NM_134000) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Act1; AI429613; CIKS |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_134000 |
| ORF Size | 1668 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR208800).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_134000.3, NP_598761.2 |
| RefSeq Size | 2867 bp |
| RefSeq ORF | 1668 bp |
| Locus ID | 103213 |
| Gene Summary | E3 ubiquitin ligase that catalyzes 'Lys63'-linked polyubiquitination of target protein, enhancing protein-protein interaction and cell signaling (By similarity). Transfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein (By similarity). Essential adapter molecule in IL17A-mediated signaling (PubMed:19825828). Upon IL17A stimulation, interacts with IL17RA and IL17RC receptor chains through SEFIR domains and catalyzes 'Lys63'-linked polyubiquitination of TRAF6, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways (PubMed:19825828).[UniProtKB/Swiss-Prot Function] |
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