United States
Germany
Japan
United Kingdom
China
Alpl (NM_007431) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR208392L3V
- LentiORF®
-
Lenti ORF particles, Alpl (Myc-DDK-tagged) - Mouse alkaline phosphatase, liver/bone/kidney (Alpl), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 9,785.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Alpl (NM_007431) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Ak; Akp; Akp-2; Akp2; ALP; APTNAP; T; TNAP; TNSALP |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_007431 |
| ORF Size | 1575 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR208392).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_007431.1 |
| RefSeq Size | 2524 bp |
| RefSeq ORF | 1575 bp |
| Locus ID | 11647 |
| Gene Summary | This gene encodes a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. The encoded protein is a membrane-bound glycosylated enzyme that catalyzes the hydrolysis of phosphate esters at alkaline pH. The mature peptide maintains the ratio of inorganic phosphate to inorganic pyrophosphate required for bone mineralization. Mice that lack this enzyme show symptoms of osteomalacia, softening of the bones. In humans, mutations in this gene are associated with hypophosphatasia, an inherited metabolic bone disease in which deficiency of this enzyme inhibits bone mineralization leading to skeletal defects. Mutations in the mouse gene mirror the symptoms of human hypophosphatasia. A pseudogene of this gene is present on chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
