Fus (NM_139149) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR208306L4V
- LentiORF®
-
Lenti ORF particles, Fus (GFP-tagged) - Mouse fusion, derived from t(12;16) malignant liposarcoma (human) (Fus), 200ul, >10^7 TU/mL
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CNY 10,830.00
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经常一起买 (2)
Specifications
Product Data | |
Product Name | Fus (NM_139149) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | D430004D17Rik; D930039C12Rik; Fus1; Tls |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_139149 |
ORF Size | 1554 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR208306).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_139149.2, NP_631888.1 |
RefSeq Size | 1845 bp |
RefSeq ORF | 1557 bp |
Locus ID | 233908 |
Gene Summary | DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response. Binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing. Binds also its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay. Plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair (By similarity). In neuronal cells, plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis (PubMed:16317045, PubMed:25968143).[UniProtKB/Swiss-Prot Function] |
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