Micu1 (NM_144822) Mouse Tagged ORF Clone Lentiviral Particle

CAT＃: MR207652L4V

LentiORF^®

Lenti ORF particles, Micu1 (GFP-tagged) - Mouse calcium binding atopy-related autoantigen 1 (Cbara1), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Datasheet

SDS

Need custom lentivirus service?
Get a free quote

CNY 10,260.00

货期*

详询

规格

Product images

经常一起买 (2)

PS100093V

Lenti ORF control particles of pLenti-C-mGFP-P2A-Puro, >1x10^7 TU/ml, 0.5 ml

CNY 2,950.00

TR30038

One-Wash Lentivirus Titer Kit, HIV-1 p24 ELISA

CNY 5,230.00

Specifications

Product Data
Product Name	Micu1 (NM_144822) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms	C730016L05Rik; Calc; Cbara1
Vector	pLenti-C-mGFP-P2A-Puro
ACCN	NM_144822
ORF Size	1434 bp
Sequence Data	ORF Nucleotide Sequence (showhide) The ORF insert of this clone is exactly the same as(MR207652).
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq	NM_144822.2
RefSeq Size	2358 bp
RefSeq ORF	1434 bp
Locus ID	216001
Gene Summary	Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains (PubMed:24560927). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulates and inhibits MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptake (By similarity). Acts as a gatekeeper of MCU at low concentration of calcium, preventing channel opening (By similarity). Enhances MCU opening at high calcium concentration, allowing a rapid response of mitochondria to calcium signals generated in the cytoplasm (PubMed:24560927). Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake (By similarity). Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG (By similarity).[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Product Manuals
TrueORFs: Open Reading Frame Clones - 10 ug in PrecisionShuttle Vector System pLenti-ORF destination vector Transfection - TurboFectin 8.0 Transfection Reagent Plasmid Preparation - PowerPrep Plasmid Purification Kits
FAQs
TrueORF Clones/PrecisionShuttle Organelle Marker Transfection Reagent
SDS
Lenti SDS

Resources

cDNA 克隆相关资源
Video Tutorial: Clone Selection Guide Product Video: What is TrueORF GOLD and why it is the most popular type of clone Video Tutorial: How to make Lentivirus particles Video Tutorial: Is the Lentivirus Safe Product Brochure: cDNA clones $98 Clones. Download the List of 15,000 Protocol: Lentivirus packaging

You may also need

Control Particles

mGFP Antibody

其它Micu1产品

Expression Plasmids

Lentiviral Particles

CRISPR

RNAi

Proteins

Antibodies