Micu1 (NM_144822) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR207652L3V
- LentiORF®
-
Lenti ORF particles, Micu1 (Myc-DDK-tagged) - Mouse calcium binding atopy-related autoantigen 1 (Cbara1), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 9,215.00
货期*
详询
规格
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (2)
Specifications
Product Data | |
Product Name | Micu1 (NM_144822) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | C730016L05Rik; Calc; Cbara1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_144822 |
ORF Size | 1434 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR207652).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_144822.2 |
RefSeq Size | 2358 bp |
RefSeq ORF | 1434 bp |
Locus ID | 216001 |
Gene Summary | Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains (PubMed:24560927). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulates and inhibits MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptake (By similarity). Acts as a gatekeeper of MCU at low concentration of calcium, preventing channel opening (By similarity). Enhances MCU opening at high calcium concentration, allowing a rapid response of mitochondria to calcium signals generated in the cytoplasm (PubMed:24560927). Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake (By similarity). Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
You may also need
Customer
Reviews
Loading...