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Wdr4 (BC039272) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR206503L4V
- LentiORF®
-
Lenti ORF particles, Wdr4 (GFP-tagged) - Mouse WD repeat domain 4 (cDNA clone MGC:35877 IMAGE:5027600), 200ul, >10^7 TU/mL
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CNY 11,115.00
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Specifications
| Product Data | |
| Product Name | Wdr4 (BC039272) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AI415180; AI448349; D530049K22Rik |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | BC039272 |
| ORF Size | 1239 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR206503).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC039272, AAH39272 |
| RefSeq Size | 2054 bp |
| RefSeq ORF | 1241 bp |
| Locus ID | 57773 |
| Gene Summary | Non-catalytic component of a methyltransferase complex required for the formation of N(7)-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs) (PubMed:29983320). In the methyltransferase complex, it is required to stabilize and induce conformational changes of the catalytic subunit (By similarity). Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (PubMed:29983320). Also required for the formation of N(7)-methylguanine at internal sites in a subset of mRNAs (By similarity). Also required for methylation of a specific subset of miRNAs, such as let-7 (By similarity). Acts as a regulator of embryonic stem cell self-renewal and differentiation (PubMed:29983320). Independently of METTL1, also plays a role in genome stability: localizes at the DNA replication site and regulates endonucleolytic activities of FEN1 (PubMed:29574139).[UniProtKB/Swiss-Prot Function] |
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